Angiogenesis-Related Biomarkers (sFlt-1/PLGF) in the Prediction and Diagnosis of Placental Dysfunction: An Approach for Clinical Integration. [revisión]
Por: Herráiz García, Ignacio [Obstetricia y Ginecología]
| Simón San José, Elisa [Obstetricia Ginecología] | Gómez Arriaga, Paula Isabel [Obstetricia y Ginecología] | Martínez-Moratalla Valcárcel, José Manuel [Obstetricia y Ginecología] | García Burguillo, Antonio [Obstetricia y Ginecología] | López Jiménez, Ana Elena [Bioquímica] | Galindo Izquierdo, Alberto [Obstetricia y Ginecología].
Colaborador(es): Servicio de Obstetricia y Ginecología | Servicio de Bioquímica Clínica.
Tipo de material: 
ArtículoEditor: International journal of molecular sciences, 2015Descripción: 16(8):19009-26.Recursos en línea: Acceso libre Resumen: Placental dysfunction is involved in a group of obstetrical conditions including preeclampsia, intrauterine growth restriction, and placental abruption. Their timely and accurate recognition is often a challenge since diagnostic criteria are still based on nonspecific signs and symptoms. The discovering of the role of angiogenic-related factors (sFlt-1/PlGF) in the underlying pathophysiology of placental dysfunction, taking into account that angiogenesis-related biomarkers are not specific to any particular placental insufficiency-related disease, has marked an important step for improving their early diagnosis and prognosis assessment. However, sFlt-1/PlGF has not been yet established as a part of most guidelines. We will review the current evidence on the clinical utility of sFlt-1/PlGF and propose a new protocol for its clinical integration.
| Tipo de ítem | Ubicación actual | Signatura | Estado | Fecha de vencimiento |
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Revisión
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PC16789 (Navegar estantería) | Disponible |
Formato Vancouver:
Herraiz I, Simón E, Gómez Arriaga PI, Martínez Moratalla JM, García Burguillo A, Jiménez EA et al. Angiogenesis-Related Biomarkers (sFlt-1/PLGF) in the Prediction and Diagnosis of Placental Dysfunction: An Approach for Clinical Integration. Int J Mol Sci. 2015 Aug 13;16(8):19009-26.
PMID: 26287164
PMC4581283
Contiene 65 referencias
Placental dysfunction is involved in a group of obstetrical conditions including preeclampsia, intrauterine growth restriction, and placental abruption. Their timely and accurate recognition is often a challenge since diagnostic criteria are still based on nonspecific signs and symptoms. The discovering of the role of angiogenic-related factors (sFlt-1/PlGF) in the underlying pathophysiology of placental dysfunction, taking into account that angiogenesis-related biomarkers are not specific to any particular placental insufficiency-related disease, has marked an important step for improving their early diagnosis and prognosis assessment. However, sFlt-1/PlGF has not been yet established as a part of most guidelines. We will review the current evidence on the clinical utility of sFlt-1/PlGF and propose a new protocol for its clinical integration.
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