Herráiz García, Ignacio Simón San José, Elisa Gómez Arriaga, Paula Isabel Martínez-Moratalla Valcárcel, José Manuel García Burguillo, Antonio López Jiménez, Ana Elena Galindo Izquierdo, Alberto
Angiogenesis-Related Biomarkers (sFlt-1/PLGF) in the Prediction and Diagnosis of Placental Dysfunction: An Approach for Clinical Integration. [revisión] - International journal of molecular sciences, 2015 - 16(8):19009-26.
Formato Vancouver:
Herraiz I, Simón E, Gómez Arriaga PI, Martínez Moratalla JM, García Burguillo A, Jiménez EA et al. Angiogenesis-Related Biomarkers (sFlt-1/PLGF) in the Prediction and Diagnosis of Placental Dysfunction: An Approach for Clinical Integration. Int J Mol Sci. 2015 Aug 13;16(8):19009-26.
PMID: 26287164
PMC4581283
Contiene 65 referencias
Placental dysfunction is involved in a group of obstetrical conditions including preeclampsia, intrauterine growth restriction, and placental abruption. Their timely and accurate recognition is often a challenge since diagnostic criteria are still based on nonspecific signs and symptoms. The discovering of the role of angiogenic-related factors (sFlt-1/PlGF) in the underlying pathophysiology of placental dysfunction, taking into account that angiogenesis-related biomarkers are not specific to any particular placental insufficiency-related disease, has marked an important step for improving their early diagnosis and prognosis assessment. However, sFlt-1/PlGF has not been yet established as a part of most guidelines. We will review the current evidence on the clinical utility of sFlt-1/PlGF and propose a new protocol for its clinical integration.
Angiogenesis-Related Biomarkers (sFlt-1/PLGF) in the Prediction and Diagnosis of Placental Dysfunction: An Approach for Clinical Integration. [revisión] - International journal of molecular sciences, 2015 - 16(8):19009-26.
Formato Vancouver:
Herraiz I, Simón E, Gómez Arriaga PI, Martínez Moratalla JM, García Burguillo A, Jiménez EA et al. Angiogenesis-Related Biomarkers (sFlt-1/PLGF) in the Prediction and Diagnosis of Placental Dysfunction: An Approach for Clinical Integration. Int J Mol Sci. 2015 Aug 13;16(8):19009-26.
PMID: 26287164
PMC4581283
Contiene 65 referencias
Placental dysfunction is involved in a group of obstetrical conditions including preeclampsia, intrauterine growth restriction, and placental abruption. Their timely and accurate recognition is often a challenge since diagnostic criteria are still based on nonspecific signs and symptoms. The discovering of the role of angiogenic-related factors (sFlt-1/PlGF) in the underlying pathophysiology of placental dysfunction, taking into account that angiogenesis-related biomarkers are not specific to any particular placental insufficiency-related disease, has marked an important step for improving their early diagnosis and prognosis assessment. However, sFlt-1/PlGF has not been yet established as a part of most guidelines. We will review the current evidence on the clinical utility of sFlt-1/PlGF and propose a new protocol for its clinical integration.
