Pérez Gómez, Eduardo
TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling. [artículo] - Mollecular & cellular oncology, 2015 - 2(3):e980134.
Formato Vancouver:
Salazar M, Lorente M, García Taboada E, Gómez EP, Dávila D, Zúñiga García P et al. TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling. Mol Cell Oncol. 2015 Apr 18;2(3):e980134.
PMID: 27308456
PMC4905291
Contiene 10 referencias
In a recent article, we found that Tribbles pseudokinase 3 (TRIB3) plays a tumor suppressor role and that this effect relies on the dysregulation of the phosphorylation of v-akt murine thymoma viral oncogene homolog (AKT) by the mammalian target of rapamycin complex 2 (mTORC2 complex), and the subsequent hyperphosphorylation and inactivation of the transcription factor Forkhead box O3 (FOXO3).
TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling. [artículo] - Mollecular & cellular oncology, 2015 - 2(3):e980134.
Formato Vancouver:
Salazar M, Lorente M, García Taboada E, Gómez EP, Dávila D, Zúñiga García P et al. TRIB3 suppresses tumorigenesis by controlling mTORC2/AKT/FOXO signaling. Mol Cell Oncol. 2015 Apr 18;2(3):e980134.
PMID: 27308456
PMC4905291
Contiene 10 referencias
In a recent article, we found that Tribbles pseudokinase 3 (TRIB3) plays a tumor suppressor role and that this effect relies on the dysregulation of the phosphorylation of v-akt murine thymoma viral oncogene homolog (AKT) by the mammalian target of rapamycin complex 2 (mTORC2 complex), and the subsequent hyperphosphorylation and inactivation of the transcription factor Forkhead box O3 (FOXO3).
