000			03444na a2200289 4500
003			H12O
005			20180113071945.0
008			130622s2012 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aspa
100			_aAguilella Vizcaíno, María José _91920 _eFarmacia
100			_aCordero Cruz, Ana María _91998 _eFarmacia
100			_aGomis Muñoz, Pilar _91450 _eFarmacia
100			_9875 _aHerreros de Tejada López-Coterilla, Alberto _eFarmacia
100			_9442 _aMoreno Villares, José Manuel _eGastroenterología y Nutrición Infantil
245	0	0	_aNutrición parenteral domiciliaria en niños en un hospital terciario entre los años 1993 y 2009 _h[artículo]
260			_bNutricion Hospitalaria, _c2012
300			_a27(1):262-265.
500			_aFormato Vancouver: Cordero Cruz AM, Aguilella Vizcaíno MJ, González Fuentes C, Rubio Murillo M, Moreno Villares JM, Gomis Muñoz P, et al. Nutrición parenteral domiciliaria en niños en un hospital terciario entre los años 1993 y 2009.. Nutr Hosp. 2012;27(1):262-5.
501			_aPMID: 22566331
504			_aContiene 27 referencias
520			_aHome parenteral nutrition (HPN) has a key role in the management of permanent or transient intestinal failure in the pediatric patient. Although its use is not without complications. We review our experience since the beginning of the program in 1993. PATIENTS AND METHODS: Longitudinal and retrospective study of the clinical records from 25 infants and children (11 boys, 14 girls) who received HPN in this period. If a patient received HPN in periods separated more than 3 months we consider a different episode. In this way, 32 episodes were described. Quantitative data are presented as mean or median and qualitative as frequency. Complications are presented as complication rate per 1,000 days of HPN. RESULTS: 16 patients started HPN younger than 1 year. Total length of HPN was 9,986 days, median 174 days (range 7 to 2,444 days). Main indication was short bowel syndrome (n = 6); motility disorders (n = 6); chronic diarrhea (n = 5), malnutrition (n = 3) and other causes (n = 5). 47 catheters were used; mean length 212.5 days, median 120 days (range: 7 to 930). Most of central venous catheters were tunnelled catheters (n = 42); subcutaneous ports (n=3) and in two cases periferically inserted central catheters (PICCS). Complication rate per 1,000 days of HPN was: 3.4 for catheter-related infections, 0.1 for obstruction; 0.9 for leakage, and 0.1 for accidental removal. Most common microorganisms were Staphylococcus coagulase negative (47%), Gram negative bacteria (21%), Staphylococcus aureus (15%), fungi (9%) and others in 9%. Parenteral nutrition-associated liver disease was present in 4 patients. 21 patients were weaned off HPN, 3 patients deceased because of underlying disease, 2 patients underwent intestinal transplantation, while 5 patients continue in the program. CONCLUSIONS: Every year two new patients enter in the program. 65% of patients were weaned off HPN. Infectious complications were the most frequent (rate 3.4 infections per 1,000 days of HPN). Mean length of HPN was 174 days, and 120 days for catheters.
710			_9446 _aServicio de Pediatría-Neonatología
710			_9320 _aServicio de Farmacia Hospitalaria
856			_uhttp://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112012000100034&lng=en&nrm=iso&tlng=en _yAcceso libre
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999			_c9760 _d9760