000			03119na a2200301 4500
003			H12O
005			20191030062655.0
008			130622s2011 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aspa
100			_aCastellano, Daniel _9882 _eOncología Médica
100			_aDíaz González, Rafael _9946 _eUrología
100			_aMedina Polo, José _91794 _eUrología
100			_9485 _aVillacampa Aubá, Felipe _eUrología
100			_91795 _aRosa Kehrman, Federico de la _eUrología
245	0	0	_aTumores testiculares: cirugía de masas retroperitoneales residuales tras tratamiento quimioterápico; ¿es posible predecir su histología? _h[artículo]
260			_bArchivos Españoles de Urología, _c2011
300			_a64(7):611-619.
337			_a
500			_aFormato Vancouver: Medina-Polo J, Martínez-Silva V, Domínguez-Esteban M, de la Rosa-Kehrmann F, Villacampa-Aubá F, Castellano-Gauna D, et al. Tumores testiculares: cirugía de masas retroperitoneales residuales tras tratamiento quimioterápico; ¿es posible predecir su histología?. Arch Esp Urol. 2011;64(7):611-9.
501			_aPMID: 21965259
504			_aContiene 25 referencias
520			_aOBJECTIVES: We present our series of residual retroperitoneal mass surgery after chemotherapy. We evaluate possible preoperative parameters that can predict the retroperitoneal mass histology. Survival and relapse rates were also evaluated. METHODS: We reviewed sixty resections of residual retroperitoneal masses of testicular tumours after chemotherapy performed at our department between 1995 and 2007. We evaluate the relationship between histology of the retroperitoneal mass and possible risk factors, such as outcomes after chemotherapy, which was evaluated as changes in the size of the retroperitoneal mass, and negativization of serum tumor markers. We also evaluate histology and size of the primary testicular cancer. RESULTS: The histology of retroperitoneal mass was necrosis or fibrosis in 25 (42%) cases, teratoma in 29 (48%) and viable tumor in 6 (10%). The size of the retroperitoneal mass decreased after the chemotherapy in 62% cases; moreover negative serum tumor markers were found in 87%. Elevated values of human chorionic gonadotropin were associated with viable cells in the retroperitoneal mass (p=0.014) and, the presence of teratoma in the primary tumor may be associated with teratoma in the retroperitoneal mass histology (p=0.002). However, no other preoperative factors that predict the residual mass histology were found. Repeated resections of retroperitoneal masses were required in four patients and 9 patients died during follow-up. CONCLUSIONS: We cannot determine preoperative parameters that accurately predict the histology of retroperitoneal masses. Therefore, resection of residual retroperitoneal masses after chemotherapy in non-seminomatous germ cell tumours must be performed.
710			_9220 _aServicio de Urología
710			_9303 _aServicio de Oncología Médica
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/8/pc8323.pdf _ySolicitar documento
942			_n0 _2ddc _cART
999			_c8323 _d8323