000			02426na a2200313 4500
003			H12O
005			20210625062807.0
008			130622s2012 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_9867 _aBarrado Blanco, Laura _eMicrobiología y Parasitología
100			_978 _aChaves Sánchez, Fernando _eMicrobiología y Parasitología
100			_91619 _aOrellana Miguel, María Ángeles _eMicrobiología y Parasitología
100			_9868 _aRodríguez Otero, Joaquín _eMicrobiología y Parasitología
100			_91506 _aSanz Sanz, Francisca _eMicrobiología y Parasitología
100			_aViedma Moreno, Esther _91616 _eInstituto de Investigación i+12
100			_aVilla García, Jennifer _92027 _eMicrobiología y Parasitología
245	0	0	_aVIM-2-producing multidrug-resistant Pseudomonas aeruginosa ST175 clone, Spain. _h[artículo]
260			_bEmerging Infectious Diseases, _c2012
300			_a18(8):1235-41.
500			_aFormato Vancouver: Viedma E, Juan C, Villa J, Barrado L, Orellana MA, Sanz F, et al. VIM-2-producing multidrug-resistant Pseudomonas aeruginosa ST175 clone, Spain. Emerg Infect Dis. 2012 Aug;18(8):1235-41.
501			_aPMID: 22840969
504			_aContiene 37 referencias
520			_aA total of 183 patients were colonized or infected with multidrug-resistant Pseudomonas aeruginosa isolates at a hospital in Spain during 2007-2010; prevalence increased over this period from 2.8% to 15.3%. To characterize these isolates, we performed molecular epidemiologic and drug resistance analysis. Genotyping showed that 104 (56.8%) isolates belonged to a single major clone (clone B), which was identified by multilocus sequence typing as sequence type (ST) 175. This clone was initially isolated from 5 patients in 2008, and then isolated from 23 patients in 2009 and 76 patients in 2010. PCR analysis of clone B isolates identified the bla(VIM-2) gene in all but 1 isolate, which harbored bla(IMP-22). ST175 isolates were susceptible to only amikacin (75%) and colistin (100%). Emergence of the ST175 clone represents a major health problem because it compromises therapy for treatment of P. aeruginosa nosocomial infections.
710			_981 _aServicio de Microbiología y Parasitología
710			_9625 _aInstituto de Investigación imas12
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/8/pc8274.pdf _ySolicitar documento
942			_n0 _2ddc _cART
999			_c8274 _d8274