000			03334na a2200313 4500
003			H12O
005			20180417112624.0
008			130622s2012 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aspa
100			_aAguilella Vizcaíno, María José _91920 _eFarmacia
100			_aGastalver Martín, Cristina _92001 _eFarmacia
100			_aGomis Muñoz, Pilar _91450 _eFarmacia
100			_aLeón Sanz, Miguel _91057 _eEndocrinología y Nutrición
100			_9442 _aMoreno Villares, José Manuel _eGastroenterología y Nutrición Infantil
100			_9383 _aValero Zanuy, María de los Ángeles _eEndocrinología y Nutrición
245	0	0	_aIncidencia de infección asociada a catéter y factores de riesgo relacionados en pacientes hospitalizados con nutrición parenteral. _h[artículo]
260			_bNutricion Hospitalaria, _c2012
300			_a27(3):889-93.
500			_aFormato Vancouver: Aguilella Vizcaíno MJ, Valero Zanuy MÁ, Gastalver Martín C, Gomis Muñoz P, Moreno Villares JM, León Sanz M. Incidencia de infección asociada a catéter y factores de riesgo relacionados en pacientes hospitalizados con nutrición parenteral. Nutr Hosp. 2012 May-Jun;27(3):889-93.
501			_aPMID: 23114951
504			_aContiene 23 referencias
520			_aIntroduction: The most severe complication of parenteral nutrition (PTN) is catheter-related infection (CRI). Objectives: To study the incidence rate and factors associated to CRI. Material and methods: 271 patients followed at the Nutrition Unit for 6 months. The composition of the PTN was calculated according to the metabolic demands. 20.3% received a lipid solution enriched with omega-3 fatty acids (SMOF Fresenius Kabi (R)) and 79.7% with olive oil (Clinoleic Baxter (R)). Results: The rate of CRI was 25 per 1,000 days of PTN (55 patients: 61.7 +/- 17.8 years, 60.3% males, 29.3 +/- 10.6 days of hospital stay and 10.4% mortality). Coagulase-negative Staphylococcus was the most frequently isolated microorganism. There were no differences by age, gender, mortality, or composition of the PTN between patients with or without infection. The patients treated with omega-3 received more calories with the PTN, at the expense of higher intake of glucose and lipids. However, the rate of infection was similar, although there was a not significant trend towards a lower infection rate when using the omega-3 composition (14.5% vs. 23.1%, respectively, p = 0.112). The duration of the nutritional support was higher in patients with CRI (13.0 +/- 9.7 vs. 9.3 +/- 8.1, p = 0.038). Total mortality (16.9%) was independent of the presence or absence of CRI (10.4% vs. 18.7%, p = 0.090) or of the use of omega-3 lipids or olive oil in the PTN (10.9% vs. 18.5%, p = 0.125). Conclusion: Patients submitted to PTN have a high rate of CRI. The presence of infection is related to the duration of the PTN, being independent of the age, gender, and composition of the solution. The use of omega-3 lipid solutions may be beneficial although further studies are needed to confirm this.
710			_9292 _aServicio de Endocrinología y Nutrición
710			_9446 _aServicio de Pediatría-Neonatología
710			_9320 _aServicio de Farmacia Hospitalaria
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/7/pc7314.pdf _ySolicitar documento
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999			_c7314 _d7314