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008 130622s2011 xxx||||| |||| 00| 0 eng d
040 _cH12O
041 _aeng
100 _9263
_aFernández Ruiz, Mario
_eMedicina Interna
245 0 0 _aFactors associated with mortality in patients with exacerbation of chronic obstructive pulmonary disease hospitalized in General Medicine departments
_h[artículo]
260 _bInternal and Emergency Medicine,
_c2011
300 _a6(1):47-54.
500 _aFormato Vancouver: Roca B, Almagro P, López F, Cabrera FJ, Montero L, Morchón D, et al. Factors associated with mortality in patients with exacerbation of chronic obstructive pulmonary disease hospitalized in General Medicine departments. Intern Emerg Med. 2011;6(1):47-54.
501 _aPMID:20886377
504 _aContiene 34 referencias
520 _aWe aim to improve knowledge on risk factors that relate to mortality in subjects with exacerbation of chronic obstructive pulmonary disease (COPD) who are hospitalized in General Medicine departments. In a cross-sectional multicenter study, by means of a logistic regression analysis, we assessed the possible association of death during hospitalization with the following groups of variables of participating patients: sociodemographic features, treatment received prior to admission and during hospitalization, COPD-related clinical features recorded prior to admission, comorbidity diagnosed prior to admission, clinical data recorded during hospitalization, laboratory results recorded during hospitalization, and electrocardiographic findings recorded during hospitalization. A total of 398 patients was included; 353 (88.7%) were male, and the median age of the patients was 75 years. Of these patients, 21 (5.3%) died during hospitalization. Only 270 (67.8%) received inhaled beta(2) agonists during hospitalization, while 162 (40.7%) received angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers. The median of predicted FEV(1) prior to admission was 42%. A total of 350 patients (87.9%) had been diagnosed with two or more comorbid conditions prior to admission. An association was found between increased risk of death during hospitalization and the previous diagnoses of pneumonia, coronary heart disease, and stroke. In conclusion, comorbidity is an important contributor to mortality among patients hospitalized in General Medicine departments because of COPD exacerbation.
710 _96
_aServicio de Medicina Interna
856 _uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/5/pc5737.pdf
_ySolicitar documento
942 _n0
_2ddc
_cART
999 _c5737
_d5737