000			02861na a2200301 4500
003			H12O
005			20210625062801.0
008			130622s2011 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_aCaballero González, Montserrat _91493 _ePsiquiatría
100			_9864 _aJurado Barba, Rosa _ePsiquiatría
100			_aMartínez Gras, María Isabel _91870 _ePsiquiatría
100			_aMorales Muñoz, Isabel _91871 _ePsiquiatría
100			_aRubio Valladolid, Gabriel _9726 _ePsiquiatría
100			_aÁlvarez del Manzano, Blanca _91872 _eInstituto de Investigación i+12
245	0	0	_aRelationship between measures of inhibitory processes in patients with schizophrenia: Role of substance abuse disorders _h[artículo]
260			_bPsychiatry Research, _c2011
300			_a190(2-3):187-192.
500			_aFormato Vancouver: Jurado-Barba R, Morales-Muñoz I, Del Manzano BÁ, Fernández-Guinea S, Caballero M, Martínez-Gras I, et al. Relationship between measures of inhibitory processes in patients with schizophrenia: role of substance abuse disorders. Psychiatry Res. 2011;190(2-3):187-92.
501			_aPMID: 21704386
504			_aContiene 69 referencias
520			_aDisruption of prepulse inhibition of the startle response (PPI) has been widely identified in patients with schizophrenia, as well as impairment in many domains of cognitive functioning. However, there is some controversy regarding the relationship between PPI and the different neuropsychological tasks assessing inhibition. This controversy may be due to the influence of other variables, such as substance abuse. We aimed to determine whether differences in inhibition in schizophrenia subjects were related to their pattern of substance use and whether there was a correlation between the changes in each process. PPI and neuropsychological functioning were studied in three groups of subjects with schizophrenia (N=73): tobacco dependents (ToD; n=22), multiple substance abusers (MSUD: n=31) and non-substance abusers (non-SUD; n=20). All subjects were assessed using PPI and neuropsychological tests (Stroop and Wisconsin Card Sorting Test [WCST]). ToD showed better pre-attentive inhibitory function compared to the other two groups, and MSUD showed lower resistance to interference. Furthermore, significant correlations were found between PR, Stroop, and WCST. Our data suggest that there is a relationship between the different tasks assessing inhibition in schizophrenia, being affected by substance abuse history. We also found differences in inhibition capacity depending on substance abuse in patients with schizophrenia.
710			_9150 _aServicio de Psiquiatría
710			_9625 _aInstituto de Investigación imas12
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/4/pc4440.pdf _ySolicitar documento
942			_n0 _2ddc _cART
999			_c4440 _d4440