000 | 01915na a2200277 4500 | ||
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_c4143 _d4143 |
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003 | PC4143 | ||
005 | 20181121085513.0 | ||
008 | 130622s2013 xxx||||| |||| 00| 0 eng d | ||
040 | _cH12O | ||
041 | _aeng | ||
100 |
_aCastellano Tortajada, Gregorio _91207 _eAparato Digestivo |
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245 | 0 | 0 |
_aFactors associated with early virological response to peginterferon-alpha-2a/ribavirin in chronic hepatitis C. _h[artículo] |
260 |
_bWorld Journal of Gastroenterology, _c2013 |
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300 | _a19(12):1943-52. | ||
500 | _aFormato Vancouver: García-Samaniego J, Romero M, Granados R, Alemán R, Jorge Juan M, Suárez D et al. Factors associated with early virological response to peginterferon-α-2a/ribavirin in chronic hepatitis C. World J Gastroenterol. 2013 Mar 8;19(12):1943-52. | ||
501 | _aPMID: 23569340 | ||
504 | _aContiene 43 referencias | ||
520 | _aAIM: To evaluate the impact of sociodemographic/clinical factors on early virological response (EVR) to peginterferon/ribavirin for chronic hepatitis C (CHC) in clinical practice. METHODS: We conducted a multicenter, cross-sectional, observational study in Hepatology Units of 91 Spanish hospitals. CHC patients treated with peginterferon alpha-2a plus ribavirin were included. EVR was defined as undetectable hepatitis C virus (HCV)-ribonucleic acid (RNA) or >= 2 log HCV-RNA decrease after 12 wk of treatment. A bivariate analysis of sociodemographic and clinical variables associated with EVR was carried out. Independent factors associated with an EVR were analyzed using a multiple regression analysis that included the following baseline demographic and clinical variables: age (<= 40 years vs > 40 years), gender, race, educational level, marital status and family status, weight, alcohol and tobacco consumption, source of HCV infection, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels, and gamma glutamyl transpeptidase (GGT) (<= 85 IU/mL vs > | ||
710 |
_9273 _aServicio de Medicina del Aparato Digestivo |
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856 |
_uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3613110/ _yAcceso libre |
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942 |
_n0 _2ddc _cART |