000			02648na a2200313 4500
003			H12O
005			20180417112300.0
008			130622s2012 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aspa
100			_9888 _aBurgués Calderón, Mar _eDermatología Médico-Quirúrgica
100			_91222 _aCastellanos González, María _eDermatología Médico-Quirúrgica y Venereología
100			_aRodríguez Peralto, José Luis _91219 _eAnatomía Patológica
100			_9884 _aHebe Petiti-Martin, Gisele _eDermatología Médico-Quirúrgica y Venereología
100			_aSanz Bueno, Jimena _91224 _eDermatología Médico-Quirúrgica y Venereología
100			_9891 _aVanaclocha Sebastián, Francisco _eDermatología Médico Quirúrgica y Venereología
100			_9885 _aVillar Buill, María _eDermatología Médico-Quirúrgica y Venereología
245	0	0	_aSarcoidosis simulando una histiocitosis no Langerhans, tratada con antagonistas del factor de necrosis tumoral alpha _h[artículo]
260			_bAnales de Pediatría, _c2012
300			_a77(4):267-271.
500			_aFormato Vancouver: Petiti Martin G, Castellanos González M, Sanz Bueno J, Burgués Calderón M, Villar Buil M, Vanaclocha F, et al. Sarcoidosis simulando una histiocitosis no Langerhans, tratada con antagonistas del factor de necrosis tumoral alpha. An Pediatr (Barc). 2012;77(4):267-71.
501			_aPMID: 22608978
504			_aContiene 18 referencias
520			_aSarcoidosis is a chronic multisystemic granulomatous disease of unknown origin. Generalised eruptive histiocytosis is a rare, benign, self-healing, non-Langerhans' cell histiocytosis (non-LCH). We report the case of an 8-year-old girl with sarcoidosis who was misdiagnosed as non-LCH. She was treated with oral corticosteroids, methotrexate and adalimumab, but there was insufficient control of ocular disease. The introduction of infliximab achieved a control of the uveitis and enabled the corticosteroid dose to be tapered. In some cases of sarcoidosis the lack of well-organised granuloma formation at the beginning of the disease, and the presence of prominent giant cells may suggest alternative diagnoses, such as non-LCH. Although the experience of tumour necrosis factor-alpha antagonists use in children with sarcoidosis is limited, these drugs may be helpful for those patients experiencing a severe and refractory disease.
710			_9145 _aServicio de Dermatología Médico-Quirúrgica y Venereología
710			_9330 _aServicio de Anatomía Patológica
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/4/pc4081.pdf _ySolicitar documento
942			_n0 _2ddc _cART
999			_c4081 _d4081