000 02192na a2200253 4500
003 H12O
005 20180417112257.0
008 130622s2010 xxx||||| |||| 00| 0 eng d
010 _a11191
022 _a0940-1334, 1433-8491
040 _cH12O
041 _aeng
100 _aSanz Fuentenebro, Francisco Javier
_91875
_ePsiquiatría
245 0 0 _aDifferent gray matter patterns in chronic schizophrenia and chronic bipolar disorder patients identified using voxel-based morphometry
_h[artículo]
260 _bEuropean Archives of Psychiatry and Clinical Neuroscience,
_c2011
300 _a261(5):313-322.
500 _aFormato Vancouver: Molina V, Galindo G, Cortés B, de Herrera AG, Ledo A, Sanz J, et al. Different gray matter patterns in chronic schizophrenia and chronic bipolar disorder patients identified using voxel-based morphometry. Eur Arch Psychiatry Clin Neurosci. 2011;261(5):313-22.
501 _aPMID: 21188405
504 _aContiene 72 referencias
520 _aGray matter (GM) volume deficits have been described in patients with schizophrenia (Sz) and bipolar disorder (BD), but to date, few studies have directly compared GM volumes between these syndromes with methods allowing for whole-brain comparisons. We have used structural magnetic resonance imaging (MRI) and voxel-based morphometry (VBM) to compare GM volumes between 38 Sz and 19 BD chronic patients. We also included 24 healthy controls. The results revealed a widespread cortical (dorsolateral and medial prefrontal and precentral) and cerebellar deficit as well as GM deficits in putamen and thalamus in Sz when compared to BD patients. Besides, a subcortical GM deficit was shown by Sz and BD groups when compared to the healthy controls, although a putaminal reduction was only evident in the Sz patients. In this comparison, the BD patients showed a limited cortical and subcortical GM deficit. These results support a partly different pattern of GM deficits associated to chronic Sz and chronic BD, with some degree of overlapping.
710 _9150
_aServicio de Psiquiatría
856 _uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/3/pc3601.pdf
_ySolicitar documento
942 _n0
_2ddc
_cART
999 _c3601
_d3601