000			nab a22 7a 4500
999			_c18005 _d18005
003			PC18005
005			20250626134332.0
008			250626b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aspa, eng
100			_91321 _aAndrés Belmonte, Amado _eNefrología
245	0	0	_aAlteraciones del metabolismo mineral, fracturas vertebrales, y calcificaciones aórticas en receptores estables de trasplante renal: papel del género (estudio EMITRAL). _h[artículo]
260			_bNefrología : publicación oficial de la Sociedad Española Nefrologia, _c2016
300			_a36(3):255-67.
500			_aFormato Vancouver: Torres A, Torregrosa V, Marcen R, Campistol JM, Arias M, Hernández D et al. Alteraciones del metabolismo mineral, fracturas vertebrales, y calcificaciones aórticas en receptores estables de trasplante renal: papel del género (estudio EMITRAL). Nefrologia. 2016 May-Jun;36(3):255-67.
501			_aPMID: 27133898
504			_aContiene 39 referencias
520			_aBackground and objectives: The relationship between mineral metabolism disorders, bone fractures and vascular calcifications in kidney transplant recipients has not been established. Method: We performed a cross-sectional study in 727 stable recipients from 28 Spanish transplant clinics. Mineral metabolism parameters, the semi-quantification of vertebral fractures and abdominal aortic calcifications were determined centrally. Results: Vitamin D deficiency (25OHD3<15ng/ml) was more common in female recipients at CKD-T stages I-III (29.6% vs 44.4%; p=0.003). The inverse and significant correlation between 25OHD3 and PTH was gender-specific and women exhibited a steeper slope than men (p=0.01). Vertebral fractures (VFx) with deformity grade ≥2 were observed in 15% of recipients. Factors related to VFx differed by gender; in males, age (OR 1.04; 95% CI 1.01-1.06) and CsA treatment (OR: 3.2; 95% CI: 1.6-6.3); in females, age (OR 1.07; 95% CI: 1.03-1.12) and PTH levels (OR per 100pg/ml increase: 1.27; 95% CI: 1.043-1.542). Abdominal aortic calcifications were common (67.2%) and related to classical risk factors but not to mineral metabolism parameters. Conclusions: Vitamin D deficiency is more common among female kidney transplant recipients at earlier CKD-T stages, and it contributes to secondary hyperparathyroidism. Prevalent vertebral fractures are only related to high serum PTH levels in female recipients.
710			_986 _aServicio de Nefrología
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc18005.pdf _ySolicitar documento
942			_2ddc _cART _n0