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008			240702b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_92411 _aMoraga, Ana _eInstituto de Investigación i+12
100			_92408 _aCuartero, María Isabel _eInstituto de Investigación i+12
100			_92941 _aPradillo, Jesús M. _eInstituto de Investigación imas12
100			_92409 _aMoro, María A _eInstituto de Investigación i+12
100			_92410 _aLizasoain, Ignacio _eInstituto de Investigación i+12
245	0	0	_aImaging the role of toll-like receptor 4 on cell proliferation and inflammation after cerebral ischemia by positron emission tomography. _h[artículo]
260			_bJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, _c2016
300			_a36(4):702-8.
500			_aFormato Vancouver: Moraga A, Gómez Vallejo V, Cuartero MI, Szczupak B, San Sebastián E, Markuerkiaga I et al. Imaging the role of toll-like receptor 4 on cell proliferation and inflammation after cerebral ischemia by positron emission tomography. J Cereb Blood Flow Metab. 2016 Apr;36(4):702-8.
501			_aPMID: 26787106 PMC4821030
504			_aContiene 21 referencias
520			_aThe influence of toll-like receptor 4 on neurogenesis and inflammation has been scarcely explored so far by using neuroimaging techniques. For this purpose, we performed magnetic resonance imaging and positron emission tomography with 3'-deoxy-3'-[(18)F]fluorothymidine and [(11)C]PK11195 at 2, 7, and 14 days following cerebral ischemia in TLR4(+/+)and TLR4(-/-)mice. MRI showed similar infarction volumes in both groups. Despite this, positron emission tomography with 3'-deoxy-3'-[(18)F]fluorothymidine and [(11)C]PK11195 evidenced an increase of neurogenesis and a decrease of inflammation in TLR4(-/-)mice after ischemia. These results evidence the versatility of neuroimaging techniques to monitor the role of toll-like receptor 4 after cerebral ischemia.
710			_9625 _aInstituto de Investigación imas12
856			_uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821030/pdf/10.1177_0271678X15627657.pdf _yAcceso libre
942			_2ddc _cART _n0