000			nab a22 7a 4500
999			_c17888 _d17888
003			PC17888
005			20240701113019.0
008			240701b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_91486 _aSegura de la Morena, Julián _eNefrología
100			_9539 _aRuilope Urioste, Luis Miguel _eNefrología
245	0	0	_aPrevalence and clinical profile among a cohort of 70,997 treated hypertensives. _h[artículo]
260			_bJournal of the American Society of Hypertension: JASH, _c2016
300			_a10(9):714-23.
500			_aFormato Vancouver: Divisón Garrote JA, Banegas JR, De la Cruz JJ, Escobar Cervantes C, De la Sierra A, Gorostidi M et al. Hypotension based on office and ambulatory monitoring blood pressure. Prevalence and clinical profile among a cohort of 70,997 treated hypertensives. J Am Soc Hypertens. 2016 Sep;10(9):714-23.
501			_aPMID: 27451950
504			_aContiene 51 referencias
520			_aWe aimed to determine the prevalence of hypotension and factors associated with the presence of this condition in treated hypertensive patients undergoing ambulatory blood pressure monitoring (ABPM). Data were taken from the Spanish ABPM Registry. Office blood pressure (BP) and ABPM were determined using validated devices under standardized conditions. Based on previous studies, hypotension was defined as office systolic/diastolic BP <110 and/or 70 mm Hg, daytime ABPM <105 and/or 65 mm Hg, nighttime ABPM <90 and/or 50 mm Hg, and 24-hour ABPM <100 and/or 60 mm Hg. Multivariable logistic regression was performed to determine the variables associated with the presence of hypotension. A total of 70,997 hypertensive patients on treatment (mean age 61.8 years, 52.5% men) were included in the study. The prevalence of hypotension was 8.2% with office BP, 12.2% with daytime ABPM, 3.9% with nighttime ABPM, and 6.8% with 24-hour ABPM. Low diastolic BP values were responsible for the majority of cases of hypotension. Some 68% of the hypotension cases detected by daytime ABPM did not correspond to hypotension according to office BP. The variables independently and consistently associated with higher likelihood of office, daytime, and 24 hour-based hypotension were age, female gender, history of ischemic heart disease, and body mass index <30 kg/m(2) (P < .05). In conclusion, in this large cohort of patients in usual daily practice, one in eight treated hypertensive patients are at risk of hypotension according to daytime BP. Two-thirds of them are not adequately identified with office BP. ABPM could be especially helpful for identifying ambulatory hypotension, in particular in patients who are older, women, or with previous ischemic heart disease where antihypertensive treatment should be especially individualized and cautious.
710			_986 _aServicio de Nefrología
710			_9625 _aInstituto de Investigación imas12
856			_u http://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17888.pdf _ySolicitar documento
942			_2ddc _cART _n0