000			nab a22 7a 4500
999			_c17865 _d17865
003			PC17865
005			20240604132832.0
008			240604b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_9417 _aGutiérrez Martínez, Eduardo _eNefrología
100			_9285 _aSevillano Prieto, Ángel Manuel _eNefrología
100			_91488 _aPraga Terente, Manuel _eNefrología
245	0	0	_aHaematuria as a risk factor for chronic kidney disease progression in glomerular diseases: A review. _h[revisión]
260			_bPediatric nephrology (Berlin, Germany), _c2016
300			_a31(4):523-33.
500			_aFormato Vancouver: Moreno JA, Yuste C, Gutiérrez E, Sevillano ÁM, Rubio Navarro A, Amaro Villalobos JM et al. Haematuria as a risk factor for chronic kidney disease progression in glomerular diseases: A review. Pediatr Nephrol. 2016 Apr;31(4):523-33.
501			_aPMID: 25980470
504			_aContiene 104 referencias
520			_aHaematuria has long been considered to be a benign condition associated with glomerular diseases. However, new evidences suggest that haematuria has a pathogenic role in promoting kidney disease progression. An increased risk for end-stage renal disease has been reported in adolescents and young adults with persistent microscopic haematuria. A persistent impairment of renal function has been also reported following macroscopic haematuria-associated acute kidney injury in immunoglobulin A nephropathy. Haematuria-induced renal damage has been related to oxidant, cytotoxic and inflammatory effects induced by haemoglobin or haem released from red blood cells. The pathophysiological origin of haematuria may be due to a more fragile and easily ruptured glomerular filtration barrier, as reported in several glomerular diseases. In this review we describe a number of the key issues associated with the epidemiology and pathogenesis of haematuria-associated diseases, provide an update of recent knowledge on the role of haematuria on renal function outcome and discuss specific therapeutic approaches in this setting. KEY SUMMARY POINTS: 1. Glomerular haematuria is a common observation in a number of renal diseases that may lead to persistent renal injury. 2. Haematuria in children differs from that in adults in specific aspects, particularly in the frequency of glomerular diseases and renal disease outcome. 3. Regular follow-up of renal function in children with isolated microhaematuria may be recommended.
710			_986 _aServicio de Nefrología
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17865.pdf _ySolicitar documento
942			_2ddc _cREV _n0