000			nab a22 7a 4500
999			_c17661 _d17661
003			PC17661
005			20230804103252.0
008			230804b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_9842 _aHinojosa Mena-Bernal, José _eNeurocirugía
100			_9841 _aPascual Martín, Beatriz _eNeurocirugía
245	0	0	_aClinical considerations and surgical approaches for low-grade gliomas in deep hemispheric locations: insular lesions. _h[revisión]
260			_bChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, _c2016
300			_a32(10):1875-93.
500			_aFormato Vancouver: Hinojosa J, Gil Robles S, Pascual B. Clinical considerations and surgical approaches for low-grade gliomas in deep hemispheric locations: insular lesions. Childs Nerv Syst. 2016 Oct;32(10):1875-93.
501			_aPMID: 27659830
504			_aContiene 109 referencias
520			_aInsula and paralimbic region represent a common location for gliomas in adulthood. However, limbic and paralimbic tumors are rare in children. Reports of pediatric insular tumors are scarce in literature, and most of them are included in adult's series, so their management and outcome can be outlined only after extracting data from these reports. Due to their predominantly low grade, they usually have a benign course for some time, what make them ideal candidates for total resection. However, their intricate location and spread to key areas, including the temporal lobe, make them a surgical challenge. The transsylvian route, with or without resection of the frontal and/or temporal operculae, which requires exposure of part or all of the insula is commonly selected for insular tumor approaches. Intraoperative functional mapping is a standard procedure for resection of central region tumors in adults. In children and young individuals, awake craniotomy is not always possible and surgical planning usually relay on functional and anatomical preoperative studies. The main goal when approaching an insular tumor is to achieve the largest extent of resection to increase overall patient survival while preserving the functional status, minimizing postoperative morbidity and increasing the quality of life. The extent of resection seems to be correlated also with the control of associated (and usually intractable) epilepsy.
710			_9446 _aServicio de Pediatría-Neonatología
710			_9312 _aServicio de Neurocirugía
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17661.pdf _ySolicitar documento
942			_2ddc _cREV _n0