000			naB a22 7a 4500
999			_c17659 _d17659
003			pc17659
005			20230803135542.0
008			230803b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_91220 _aMartínez González, Miguel Ángel _eAnatomía Patológica
245	0	0	_aClear Cell Atypical Fibroxanthoma: Clinicopathological Study of 6 Cases and Review of the Literature With Special Emphasis on the Differential Diagnosis. _h[revisión]
260			_bThe American Journal of dermatopathology, _c2016
300			_a38(8):586-92.
500			_aFormato Vancouver: Tardío JC, Pinedo F, Aramburu JA, Martínez González MÁ, Arias D, Khedaoui R et al. Clear Cell Atypical Fibroxanthoma: Clinicopathological Study of 6 Cases and Review of the Literature With Special Emphasis on the Differential Diagnosis. Am J Dermatopathol. 2016 Aug;38(8):586-92.
501			_aPMID: 26848640
504			_aContiene 42 referencias
520			_aAtypical fibroxanthoma (AFX) is an uncommon dermal-based neoplasm arising on the sun-damaged skin of elderly people. Clear cell AFX is a rare variant with only 12 cases reported until the present date, all of them as case reports, except for 1 small series of 3 cases. The authors report 6 new cases and review the literature with special emphasis on the differential diagnosis. The clear cell variant represents 5% of AFX from their files. Histopathologically, it consists of sheets of epithelioid, pleomorphic cells, intermixed with a varying number of giant multinucleated and spindle cells, the latter arranged in a fascicular pattern. All cell types predominantly exhibit a clear, microvacuolated cytoplasm with well-demarcated cell borders. The clinical and immunohistochemical features of this variant are similar to those of the classic type. Clear cell AFX must be differentiated from other cutaneous clear cell neoplasms, some of them with an aggressive clinical behavior, including clear cell melanoma, primary cutaneous and metastatic clear cell carcinomas, clear cell sarcoma, pleomorphic liposarcoma, tumor of perivascular epithelioid cells, and distinctive dermal clear cell mesenchymal neoplasm. The clinical presentation and immunohistochemical profile play a key role in the differential diagnosis.
710			_9330 _aServicio de Anatomía Patológica
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17659.pdf _ySolicitar documento
942			_2ddc _cREV _n0