000			nab a22 7a 4500
999			_c17201 _d17201
003			PC17201
005			20230209120218.0
008			230209b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aspa
100			_93174 _aPeña Sánchez, María Carmen _eOncología Radioterápica
245	0	0	_aNutrientes y radioterapia: revisión de la literatura. _h[revisión]
260			_bNutrición hospitalaria, _c2015
300			_a32(6):2446-59.
500			_aFormato Vancouver: Luna J, Amaya E, de Torres MV, Peña MC, Prieto I. Nutrientes y radioterapia: revisión de la literatura. Nutr Hosp. 2015 Dec 1;32(6):2446-59.
501			_aPMID: 26667691
504			_aContiene 93 referencias
520			_aIntroduction: nutrition is an important influence on treatments and quality of life of cancer patients. The relationship between different nutritional components and radiotherapy is today a topic of growing interest. Objective: to evaluate the influence of macro and micronutrients on tolerance and effectiveness of radiotherapy and their role in modulating chronic toxicity. Materials and methods: we performed a research of the published literature by consulting the MEDLINE database and Cochrane Library online between 1995 and 2015, relevant publications based on impact factor were selected. Data from the analyzed studies were exposed in sections by type of nutrient. Results: most of the studies showed common features: small sample sizes, high heterogeneity, underpowered results and few prospective randomized studies. In the section of fiber, its use in prophylaxis and treatment of radiation enteritis has been successfully evaluated in some studies, although evidence of its recommendation is still weak. Omega 3 and omega 6 fatty acids have a high metabolic potential, however the evidence regarding this benefit is limited to observational studies in certain tumors. Among the amino acids, glutamine is the most studied, and controversial results of its effect on mucositis, esophagitis and radiation enteritis were found. Vitamins and minerals are a heterogeneous group of substances that showed potential benefit due to their antioxidant activity and their supposed protector effect against toxicity secondary to radiotherapy. Ketogenic diets are beginning to be clinically studied after promising preclinical results. Conclusions: the analyzed studies show controversial or inconclusive results regarding the influence of nutrients in the radiotherapy. It has been not found Sorong evidence about their role in patients receiving ionizing radiation. Well-designed, prospective and randomized studies are needed to establish recommendations.
710			_9302 _aServicio de Oncología Radioterápica
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc17201.pdf _ySolicitar documento
942			_2ddc _cREV _n0