000			nab a22 7a 4500
999			_c16859 _d16859
003			PC16859
005			20220518130139.0
008			220518b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_92581 _aRobles Díaz, Luis _eOncología Médica
245	0	0	_aClinical guideline seom: hereditary colorectal cancer. _h[artículo]
260			_bClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, _c2015
300			_a17(12):962-71.
500			_aFormato Vancouver: Guillén Ponce C, Serrano R, Sánchez Heras AB, Teulé A, Chirivella I, Martín T et al. Clinical guideline seom: hereditary colorectal cancer. Clin Transl Oncol. 2015 Dec;17(12):962-71.
501			_aPMID: 26586118 PMC4689750
504			_aContiene 43 referencias
520			_aGenetic mutations have been identified as the cause of inherited cancer risk in some colon cancer; these mutations are estimated to account for only 5-6 % of colorectal cancer (CRC) cases overall. Up to 25-30 % of patients have a family history of CRC that suggests a hereditary component, common exposures among family members, or a combination of both. Cancers in people with a hereditary predisposition typically occur at an earlier age than in sporadic cases. A predisposition to CRC may include a predisposition to other cancers, such as endometrial cancer. We describe genetics, current diagnosis and management of CRC hereditary syndromes pointing to a multidisciplinary approach to achieve the best results in patients and family outcomes.
710			_9303 _aServicio de Oncología Médica
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc16859.pdf _ySolicitar documento
942			_2ddc _cART _n0