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999			_c15974 _d15974
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008			200609b xxu||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_91459 _aLópez Villar, Elena _eInstituto de Investigación i+12
100			_92670 _aLópez Pascual, Juan _eHematología y Hemoterapia
245	0	0	_aClinical proteomics and OMICS clues useful in translational medicine research. _h[artículo]
260			_bProteome science, _c2014
300			_a10(1):35.
500			_aFormato Vancouver: López E, Madero L, López-Pascual J, Latterich M. Clinical proteomics and OMICS clues useful in translational medicine research. Proteome Sci. 2012 May 29;10(1):35.
501			_aPMID: 22642823 PMC3536680
504			_aContiene 71 resultados
520			_aSince the advent of the new proteomics era more than a decade ago, large-scale studies of protein profiling have been used to identify distinctive molecular signatures in a wide array of biological systems, spanning areas of basic biological research, clinical diagnostics, and biomarker discovery directed toward therapeutic applications. Recent advances in protein separation and identification techniques have significantly improved proteomic approaches, leading to enhancement of the depth and breadth of proteome coverage.Proteomic signatures, specific for multiple diseases, including cancer and pre-invasive lesions, are emerging. This article combines, in a simple manner, relevant proteomic and OMICS clues used in the discovery and development of diagnostic and prognostic biomarkers that are applicable to all clinical fields, thus helping to improve applications of clinical proteomic strategies for translational medicine research.
710			_9625 _aInstituto de Investigación imas12
710			_9297 _aServicio de Hematología y Hemoterapia
856			_uhttp://europepmc.org/article/MED/22642823 _yAcceso libre
942			_2ddc _cART _n0