000			03671na a2200277 4500
003			PC1412
005			20180417112919.0
008			130622s2012
040			_cH12O
041			_aspa
100			_aRodríguez Gil, Yolanda _9855 _eAnatomía Patológica
100			_aPérez Barrios, Andrés _9856 _eAnatomía Patológica
100			_aAlberti Masgrau, Nuria _9857 _eAnatomía Patológica
100			_aGarzón Martín, Alfredo _9858 _eAnatomía Patológica
100			_9859 _aAgustín de Agustín, Pedro de _eAnatomía Patológica
245	0	0	_aFine-needle aspiration cytology diagnosis of metastatic nonhaematological neoplasms of the breast: A series of seven cases _h[artículo]
260			_bDiagnostic Cytopathology, _c2012.
300			_a40(4):297-304.
500			_aFormato Vancouver: Rodríguez Gil Y, Pérez Barrios A, Alberti Masgrau N, Garzón A, Agustín P. Fine-needle aspiration cytology diagnosis of metastatic nonhaematological neoplasms of the breast: a series of seven cases. Diagn Cytopathol. 2012;40(4):297-304.
501			_aPMID: 22431317
504			_aContiene 27 referencias, 12 figuras y 2 tablas.
520			_aResumen: Metastatic neoplasms of the breast are rare. Mammary metastases as the initial presentation are even more infrequent and can simulate a primary malignancy clinically and radiologically. Recognition of metastatic tumors in the breast is important because it would prevent unnecessary mutilating surgery and would lead to appropriate treatment of the primary tumor. There is a broad variety of cytological appearances reported about primary tumors and few reports about secondary breast malignancies, specially diagnosed by FNAC. This study was carried out to examine the clinical and cytomorphologic features of metastatic breast tumors found in 12 de Octubre University Hospital during a period of 20 years. It confirms the utility of FNAC and describes findings that can help in the differential diagnosis that sometimes can be very difficult. Seven cases of nonhematological metastatic neoplasms of the breast were identified from the files of the Department of Pathology of the 12 de Octubre University Hospital from a total of 64,000 aspirates. We included only metastatic tumors from extramammary nonhematological neoplasms. There were nine cases of hematological metastatic neoplasm that were excluded. They were diagnosed with FNAC and confirmed by histopathology, with at least three years of follow up. The breast lump was the first manifestation of malignancy in one case of synovial sarcoma. The other six cases had been previously diagnosed of cancer. These included one malignant melanoma, one alveolar rhabdomyosarcoma, one mixed müllerian tumor, one medullary carcinoma of thyroid, one colonic adenocarcinoma, and one gastric adenocarcinoma. The period of time between primary tumor and metastases ranged from one month to eight years. An accurate cytologic diagnosis was made in all the cases. Immunocytochemistry was available but diagnosis could be made with cytomorphology alone in the seven cases. Fine-needle aspiration cytology is an excellent first line diagnostic modality that is particularly informative when clinical previous data are known. If metastatic disease is suspected, the material obtained by FNAC may provide a definitive diagnosis and prevent open surgical biopsy or mastectomy. We concur with previous reports that FNAC is a reliable, rapid, secure, and cost-effective approach to the diagnosis of palpable metastatic breast tumors.
710			_9330 _aServicio de Anatomía Patológica
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc1412.pdf _ySolicitar documento
942			_2ddc _cART _n0
999			_c1412 _d1412