000			03440na a2200505 4500
999			_c112 _d112
003			PC112
005			20181204125345.0
008			130622s2013 xxx||||| |||| 00| 0 eng d
040			_cH12O
041			_aeng
100			_aRuilope Urioste, Luis Miguel _9539 _eNefrología
245	0	0	_aInternational Expert Consensus Statement Percutaneous Transluminal Renal Denervation for the Treatment of Resistant Hypertension. _h[artículo]
260			_bJournal of the American College of Cardiology, _c2013
300			_a62(22):2031-45.
500			_aFormato Vancouver: Schlaich MP, Schmieder RE, Bakris G, Blankestijn PJ, Böhm M, Campese VM et al. International expert consensus statement: Percutaneous transluminal renal denervation for the treatment of resistant hypertension. J Am Coll Cardiol. 2013 Dec 3;62(22):2031-45.
501			_aPMID: 24021387
504			_aContiene 63 referencias
520			_aCatheter-based radiofrequency ablation technology to disrupt both efferent and afferent renal nerves has recently been introduced to clinical medicine after the demonstration of significant systolic and diastolic blood pressure reductions. Clinical trial data available thus far have been obtained primarily in patients with resistant hypertension, defined as standardized systolic clinic blood pressure >= 160 mm Hg (or >= 150 mm Hg in patients with type 2 diabetes) despite appropriate pharmacologic treatment with at least 3 antihypertensive drugs, including a diuretic agent. Accordingly, these criteria and blood pressure thresholds should be borne in mind when selecting patients for renal nerve ablation. Secondary forms of hypertension and pseudoresistance, such as nonadherence to medication, intolerance of medication, and white coat hypertension, should have been ruled out, and 24-h ambulatory blood pressure monitoring is mandatory in this context. Because there are theoretical concerns with regard to renal safety, selected patients should have preserved renal function, with an estimated glomerular filtration rate >= 45 ml/min/1.73 m(2). Optimal periprocedural management of volume status and medication regimens at specialized and experienced centers equipped with adequate infrastructure to cope with potential procedural complications will minimize potential patient risks. Long-term safety and efficacy data are limited to 3 years of follow-up in small patient cohorts, so efforts to monitor treated patients are crucial to define the long-term performance of the procedure. Although renal nerve ablation could have beneficial effects in other conditions characterized by elevated renal sympathetic nerve activity, its potential use for such indications should currently be limited to formal research studies of its safety and efficacy. (J Am Coll Cardiol 2013; 62: 2031-45).
710			_986 _aServicio de Nefrología
856			_uhttp://pc-h12o-es.m-hdoct.a17.csinet.es/pdf/pc/1/pc112.pdf _ySolicitar documento
942			_n0 _2ddc _cART