Vitamin D3 receptor ( VDR ) gene rs2228570 (Fok1) and rs731236 (Taq1) variants are not associated with the risk for multiple sclerosis: results of a new study and a meta-analysis. [artículo]
Por: Benito León, Julián [Neurología]
| Calleja Castaño, Patricia [Neurología] | Díaz Sánchez, María [Neurología].
Colaborador(es): Servicio de Neurología-Neurofisiología.
Editor: PloS One, 2013Descripción: 8(6):e65487.Recursos en línea: Acceso libre Resumen: BACKGROUND: Some epidemiological, genetic, and experimental data suggest a possible role of vitamin D in the pathogenesis of multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis. Data on the possible contribution of several single nucleotide polymorphisms (SNP) in the vitamin D receptor (VDR) gene to the risk for MS are controversial. Several studies suggested an interaction between some SNPs in the VDR gene and HLADRB1*1501 in the risk for MS.
| Tipo de ítem | Ubicación actual | Signatura | Estado | Fecha de vencimiento |
|---|---|---|---|---|
Artículo
|
PC2990 (Navegar estantería) | Disponible |
Formato Vancouver:
García-Martín E, Agúndez JA, Martínez C, Benito-León J, Millán-Pascual J, Calleja P et al. Vitamin D3 receptor ( VDR ) gene rs2228570 (Fok1) and rs731236 (Taq1) variants are not
associated with the risk for multiple sclerosis: results of a new study and a meta-analysis. PLoS One. 2013 Jun 20;8(6):e65487.
PMID: 23840333
Contiene 30 referencias
BACKGROUND: Some epidemiological, genetic, and experimental data suggest a possible role of vitamin D in the pathogenesis of multiple sclerosis (MS) and in experimental autoimmune encephalomyelitis. Data on the possible contribution of several single nucleotide polymorphisms (SNP) in the vitamin D receptor (VDR) gene to the risk for MS are controversial. Several studies suggested an interaction between some SNPs in the VDR gene and HLADRB1*1501 in the risk for MS.
No hay comentarios para este ejemplar.