iPSCs, a Future Tool for Therapeutic Intervention in Mitochondrial Disorders: Pros and Cons. [artículo]
Por: Galera, Teresa [Instituto de Investigación imas12]
| Zurita, Francisco [Instituto de Investigación imas12] | Garesse, Rafael [Instituto de Investigación i+12] | Gallardo, María Esther [Instituto de Investigación i+12].
Colaborador(es): Instituto de Investigación imas12.
Tipo de material: 
ArtículoEditor: Journal of cellular physiology, 2016Descripción: 231(11):2317-8.Recursos en línea: Solicitar documento Resumen: Mitochondrial disorders, although individually are rare, taken together constitute a big group of diseases that share a defect in the oxidative phosphorylation system. Up to now, the development of therapies for these diseases is very slow and ineffective due in part to the lack of appropriate disease models. Therefore, there is an urgent need for the discovery of new therapeutic interventions. Regarding this, the generation of induced pluripotent stem cells (iPSCs) has opened new expectations in the regenerative medicine field. However, special cares and considerations must be taken into account previous to a replacement therapy. J. Cell. Physiol. 231: 2317- 23188, 2016.
| Tipo de ítem | Ubicación actual | Signatura | Estado | Fecha de vencimiento |
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Artículo
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PC17944 (Navegar estantería) | Disponible |
Navegando Hospital Universitario 12 de Octubre Estantes Cerrar el navegador de estanterías
Formato Vancouver:
Galera T, Zurita-Díaz F, Garesse R, Gallardo ME. iPSCs, a Future Tool for Therapeutic Intervention in Mitochondrial Disorders: Pros and Cons. J Cell Physiol. 2016 Nov;231(11):2317-8.
PMID: 27018482
Contiene 13 referencias
Mitochondrial disorders, although individually are rare, taken together constitute a big group of diseases that share a defect in the oxidative phosphorylation system. Up to now, the development of therapies for these diseases is very slow and ineffective due in part to the lack of appropriate disease models. Therefore, there is an urgent need for the discovery of new therapeutic interventions. Regarding this, the generation of induced pluripotent stem cells (iPSCs) has opened new expectations in the regenerative medicine field. However, special cares and considerations must be taken into account previous to a replacement therapy. J. Cell. Physiol. 231: 2317- 23188, 2016.
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