H2 -Fueled ATP Synthesis on an Electrode: Mimicking Cellular Respiration. [artículo]
Por: Natale, Paolo [Instituto de Investigación imas12]
| López Montero, Iván [Instituto de Investigación imas12].
Colaborador(es): Instituto de Investigación imas12.
Tipo de material: 
ArtículoEditor: Angewandte Chemie, 2016Descripción: 55(21):6216-20.Recursos en línea: Acceso libre Resumen: ATP, the molecule used by living organisms to supply energy to many different metabolic processes, is synthesized mostly by the ATPase synthase using a proton or sodium gradient generated across a lipid membrane. We present evidence that a modified electrode surface integrating a NiFeSe hydrogenase and a F1 F0 -ATPase in a lipid membrane can couple the electrochemical oxidation of H2 to the synthesis of ATP. This electrode-assisted conversion of H2 gas into ATP could serve to generate this biochemical fuel locally when required in biomedical devices or enzymatic synthesis of valuable products.
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Artículo
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Navegando Hospital Universitario 12 de Octubre Estantes Cerrar el navegador de estanterías
Formato Vancouver:
Gutiérrez Sanz Ó, Natale P, Márquez I, Marques MC, Zacarias S, Pita M et al. H2 -Fueled ATP Synthesis on an Electrode: Mimicking Cellular Respiration. Angew Chem Int Ed Engl. 2016 May 17;55(21):6216-20.
PMID: 26991333
PMC5132028
Contiene 28 referencias
ATP, the molecule used by living organisms to supply energy to many different metabolic processes, is synthesized mostly by the ATPase synthase using a proton or sodium gradient generated across a lipid membrane. We present evidence that a modified electrode surface integrating a NiFeSe hydrogenase and a F1 F0 -ATPase in a lipid membrane can couple the electrochemical oxidation of H2 to the synthesis of ATP. This electrode-assisted conversion of H2 gas into ATP could serve to generate this biochemical fuel locally when required in biomedical devices or enzymatic synthesis of valuable products.
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