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Generation of a human iPSC line from a patient with a defect of intergenomic communication. [artículo]

Por: Zurita, Francisco [Instituto de Investigación imas12] | Galera, Teresa [Instituto de Investigación imas12] | González Páramos, Cristina [Instituto de Investigación imas12] | Moreno Izquierdo, Ana [Genética] | Garesse, Rafael [Instituto de Investigación i+12] | Gallardo, María Esther [Instituto de Investigación i+12].
Colaborador(es): Instituto de Investigación imas12.
Tipo de material: materialTypeLabelArtículoEditor: Stem cell research, 2016Descripción: 16(1):120-3.Recursos en línea: Solicitar documento Resumen: Human iPSC line PG64SV.2 was generated from fibroblasts of a patient with a defect of intergenomic communication. This patient harbored a homozygous mutation (c.2243G>C; p.Trp748Ser) in the gene encoding the catalytic subunit of the mitochondrial DNA polymerase gamma gene (POLG). Reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using a non integrative methodology that involves the use of Sendai virus.
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Formato Vancouver:
Zurita F, Galera T, González Páramos C, Moreno Izquierdo A, Schneiderat P, Fraga MF et al. Generation of a human iPSC line from a patient with a defect of intergenomic communication. Stem Cell Res. 2016 Jan;16(1):120-3.

PMID: 27345795

Contiene 3 referencias

Human iPSC line PG64SV.2 was generated from fibroblasts of a patient with a defect of intergenomic communication. This patient harbored a homozygous mutation (c.2243G>C; p.Trp748Ser) in the gene encoding the catalytic subunit of the mitochondrial DNA polymerase gamma gene (POLG). Reprogramming factors Oct3/4, Sox2, Klf4, and cMyc were delivered using a non integrative methodology that involves the use of Sendai virus.

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