Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis. [artículo]
Por: Carreira Delgado, Patricia Esmeralda [Reumatología]
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Colaborador(es): Servicio de Reumatología.
Editor: Annals of the Rheumatic Diseases, 2012Descripción: 71(1):114-9.Recursos en línea: Solicitar documento Resumen: OBJECTIVE: Systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) are related chronic autoimmune diseases of complex aetiology in which the interferon (IFN) pathway plays a key role. Recent studies have reported an association between IRF7 and SLE which confers a risk to autoantibody production. A study was undertaken to investigate whether the IRF7 genomic region is also involved in susceptibility to SSc and the main clinical features.
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Artículo
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Formato Vancouver:
Carmona FD, Gutala R, Simeón CP, Carreira P, Ortego-Centeno N, Vicente-Rabaneda E, et al. Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis. Ann Rheum Dis. 2012 Jan;71(1):114-9.
PMID: 21926187
Contiene 34 referencias
OBJECTIVE: Systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) are related chronic autoimmune diseases of complex aetiology in which the interferon (IFN) pathway plays a key role. Recent studies have reported an association between IRF7 and SLE which confers a risk to autoantibody production. A study was undertaken to investigate whether the IRF7 genomic region is also involved in susceptibility to SSc and the main clinical features.
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