The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity?. [artículo]
Por: Pareja Galeano, Helios [Instituto de Investigación imas12]
| Lucía, Alejandro [Instituto de Investigación i+12].
Colaborador(es): Instituto de Investigación imas12.
Tipo de material: 
ArtículoEditor: Aging cell, 2015Descripción: 14(6):921-3.Recursos en línea: Acceso libre Resumen: Mitochondrial-derived peptides (MDP) are encoded by functional short open reading frames in the mitochondrial DNA (mtDNA). These include humanin, and the recently discovered mitochondrial open reading frame of the 12S rRNA-c (MOTS-c). Although more research is needed, we suggest that the m.1382A>C polymorphism located in the MOTS-c encoding mtDNA, which is specific for the Northeast Asian population, may be among the putative biological mechanisms explaining the high longevity of Japanese people.
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Artículo
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PC17415 (Navegar estantería) | Disponible |
Formato Vancouver:
Fuku N, Pareja Galeano H, Zempo H, Alis R, Arai Y, Lucía A et al. The mitochondrial-derived peptide MOTS-c: a player in exceptional longevity? Aging Cell. 2015 Dec;14(6):921-3.
PMID: 26289118
PMC4693465
Contiene 22 referencias
Mitochondrial-derived peptides (MDP) are encoded by functional short open reading frames in the mitochondrial DNA (mtDNA). These include humanin, and the recently discovered mitochondrial open reading frame of the 12S rRNA-c (MOTS-c). Although more research is needed, we suggest that the m.1382A>C polymorphism located in the MOTS-c encoding mtDNA, which is specific for the Northeast Asian population, may be among the putative biological mechanisms explaining the high longevity of Japanese people.
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