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Serum eicosapentaenoic acid to arachidonic acid ratio is associated with cardio-healthy exceptional longevity. [artículo]

Por: Pareja Galeano, Helios [Instituto de Investigación imas12] | Sanchis Gomar, Fabián [Instituto de Investigación imas12] | Santos Lozano, Alejandro [Instituto de Investigación i+12] | Fiuza Luces, Carmen [Instituto de Investigación i+12] | Lucía, Alejandro [Instituto de Investigación i+12].
Colaborador(es): Instituto de Investigación imas12.
Tipo de material: materialTypeLabelArtículoEditor: International journal of cardiology, 2015Descripción: 184:655-656.Recursos en línea: Solicitar documento Resumen: Background: An association between head trauma and essential tremor (ET) has not been formally assessed. Our purpose was to assess the association between serious head trauma and ET. Methods: History of head trauma was assessed in 274 ET cases and 3201 controls in the Neurological Disorders in Central Spain (NEDICES) study, a population-based study in central Spain. Head trauma was defined as serious only if the subject reported that the trauma resulted in loss of consciousness, hospitalization, or a visit to the emergency department. Results: Thirty-two (11.7%) of 274 ET cases vs. 260 (8.1%) of 3201 controls reported a history of serious head trauma (p=0.04). In an adjusted logistic regression analysis, participants who reported serious head trauma were 52% more likely to have ET (odds ratio [OR] 1.52; 95% confidence interval [CI] 1.02-2.27, p=0.04). The odds of ET increased with increasing age of head trauma: adjusted ORs=1.23 (95% CI 0.43-3.46, p = 0.70) for serious head trauma that occurred before age 18 years, adjusted OR=1.49 (95% CI 0.62-3.55, p = 0.37) for serious head trauma between ages 18 to 39 years, and adjusted OR=1.61 (95% CI 1.00-2.57, p = 0.04) for serious head trauma at age 40 years or older. Conclusions: Our study suggests that serious head trauma, especially when it occurs after 40 years, is associated with increased odds of ET. Additional studies are needed to reproduce this novel finding.
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Formato Vancouver:
Pareja Galeano H, Sanchís Gomar F, Santos Lozano A, Garatachea N, Fiuza Luces C, Lucia A et al. Serum eicosapentaenoic acid to arachidonic acid ratio is associated with cardio-healthy exceptional longevity. Int J Cardiol. 2015 Apr 1;184:655-656.

PMID: 25771232

Contiene 10 referencias

Background: An association between head trauma and essential tremor (ET) has not been formally assessed. Our purpose was to assess the association between serious head trauma and ET.
Methods: History of head trauma was assessed in 274 ET cases and 3201 controls in the Neurological Disorders in Central Spain (NEDICES) study, a population-based study in central Spain. Head trauma was defined as serious only if the subject reported that the trauma resulted in loss of consciousness, hospitalization, or a visit to the emergency department.
Results: Thirty-two (11.7%) of 274 ET cases vs. 260 (8.1%) of 3201 controls reported a history of serious head trauma (p=0.04). In an adjusted logistic regression analysis, participants who reported serious head trauma were 52% more likely to have ET (odds ratio [OR] 1.52; 95% confidence interval [CI] 1.02-2.27, p=0.04). The odds of ET increased with increasing age of head trauma: adjusted ORs=1.23 (95% CI 0.43-3.46, p = 0.70) for serious head trauma that occurred before age 18 years, adjusted OR=1.49 (95% CI 0.62-3.55, p = 0.37) for serious head trauma between ages 18 to 39 years, and adjusted OR=1.61 (95% CI 1.00-2.57, p = 0.04) for serious head trauma at age 40 years or older.
Conclusions: Our study suggests that serious head trauma, especially when it occurs after 40 years, is associated with increased odds of ET. Additional studies are needed to reproduce this novel finding.

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