Results of kidney transplantation from deceased donors with acute kidney injury. [artículo]
Por: Molina Gómez, María [Nefrología]
| Apaza Chávez, Jacqueline [Nefrología] | González Monte, Esther [Nefrología] | Gutiérrez Martínez, Eduardo [Nefrología] | Sevillano Prieto, Ángel Manuel [Nefrología] | Polanco Fernández, Natalia [Nefrología] | Hernández, Ana [Nefrología] | Praga Terente, Manuel [Nefrología] | Andrés Belmonte, Amado [Nefrología].
Colaborador(es): Servicio de Nefrología.
Tipo de material: 
ArtículoEditor: Transplantation proceedings, 2015Descripción: 47(1):42-4.Recursos en línea: Solicitar documento Resumen: Background: Different strategies have been initiated to shorten the waiting list time to receive a kidney transplant. Donors with acute kidney injury (AKI) may be a new option.
Methods: Fifty-nine patients received a kidney transplant from an AKI donor defined as having serum creatinine >2 mg/dL at the time of organ procurement. They were compared with a transplant group with normal kidney function defined as creatinine <1.5 mg/dL organ procurement in the same time period, paired by donor and recipient age (control group). Initial evolution, at 1 year, and at the end of the follow-up were evaluated.
Results: The AKI donor group had greater delayed graft function (68% versus 36%, P < .01). Graft and recipient survival were similar in both groups at 1 year (92% versus 88%, P = NS; 97% versus 98%, P = NS) and at the end of follow-up (66% versus 66%, P = NS; 90% versus 88%, P = NS). Serum creatinine at 1 year and at the end of the follow-up did not show any differences (1.4 ± 0.5 versus 1.4 ± 0.7 mg/dL, P = NS; 1.4 ± 0.5 versus 1.6 ± 0.9 mg/dL, P = NS).
Conclusions: The transplants from donors with AKI showed greater incidence of delayed graft function, but this did not affect the short- or long-term prognosis of the graft or recipient. This type of donor may be a source of acceptable kidneys.
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Formato Vancouver:
Molina M, Apaza J, González Monte E, Gutiérrez Martínez E, Sevillano AM, Marín JP et al. Results of kidney transplantation from deceased donors with acute kidney injury. Transplant Proc. 2015 Jan-Feb;47(1):42-4.
PMID: 25645766
Contiene 16 referencias
Background: Different strategies have been initiated to shorten the waiting list time to receive a kidney transplant. Donors with acute kidney injury (AKI) may be a new option.
Methods: Fifty-nine patients received a kidney transplant from an AKI donor defined as having serum creatinine >2 mg/dL at the time of organ procurement. They were compared with a transplant group with normal kidney function defined as creatinine <1.5 mg/dL organ procurement in the same time period, paired by donor and recipient age (control group). Initial evolution, at 1 year, and at the end of the follow-up were evaluated.
Results: The AKI donor group had greater delayed graft function (68% versus 36%, P < .01). Graft and recipient survival were similar in both groups at 1 year (92% versus 88%, P = NS; 97% versus 98%, P = NS) and at the end of follow-up (66% versus 66%, P = NS; 90% versus 88%, P = NS). Serum creatinine at 1 year and at the end of the follow-up did not show any differences (1.4 ± 0.5 versus 1.4 ± 0.7 mg/dL, P = NS; 1.4 ± 0.5 versus 1.6 ± 0.9 mg/dL, P = NS).
Conclusions: The transplants from donors with AKI showed greater incidence of delayed graft function, but this did not affect the short- or long-term prognosis of the graft or recipient. This type of donor may be a source of acceptable kidneys.
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