Pulmonary vasodilator therapy and early postoperative outcome after modified Fontan operation. [artículo]
Por: Mendoza Soto, Alberto [Pediatría]
| Albert de la Torre, Leticia [Pediatría] | Belda Hofheinz, Sylvia [Pediatría] | Casanueva Mateos, Lidia [Pediatría] | Herrera Linde, María Dolores [Cardiología] | Granados Ruiz, Miguel Ángel [Pediatría] | Velasco Bayón, José Manuel [Cardiología] | García, Enrique [Pediatría] | Aguilar, J.M [Pediatría] | Comas Illas, Juan Valentín [Cirugía Cardíaca Pediátrica].
Colaborador(es): Servicio de Pediatría-Neonatología | Unidad de Cuidados Intensivos Pediátricos.
Tipo de material: 
ArtículoEditor: Cardiology in the young, 2015Descripción: 25(6):1136-40.Recursos en línea: Solicitar documento Resumen: Although mortality is low after the modified Fontan procedure, there is a significant percentage of patients with prolonged postoperative recovery. The objective of this study is to evaluate the usefulness of postoperative administration of oral sildenafil and inhaled nitric oxide on early postoperative outcome. A prospective interventional and comparison study with a historical cohort was conducted. Between January, 2010 and March, 2013, 16 patients received oral sildenafil during immediate modified Fontan postoperative period. Inhaled nitric oxide was also administered if the patient was kept intubated 12 hours after surgery. Early postoperative outcome was compared with a historical cohort of 32 patients on whom the modified Fontan procedure was performed between March, 2000 and December, 2009. Postoperative administration of sildenafil and nitric oxide had no influence on early postoperative outcome after the modified Fontan procedure in terms of duration of pleural effusions, mechanical ventilation time, length of stay in the ICU, and length of hospital stay.
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Formato Vancouver:
Mendoza A, Albert L, Belda S, Casanueva L, Herrera D, Granados MA et al. Pulmonary vasodilator therapy and early postoperative outcome after modified Fontan operation. Cardiol Young. 2015 Aug;25(6):1136-40.
PMID: 25225716
Contiene 39 referencias
Although mortality is low after the modified Fontan procedure, there is a significant percentage of patients with prolonged postoperative recovery. The objective of this study is to evaluate the usefulness of postoperative administration of oral sildenafil and inhaled nitric oxide on early postoperative outcome. A prospective interventional and comparison study with a historical cohort was conducted. Between January, 2010 and March, 2013, 16 patients received oral sildenafil during immediate modified Fontan postoperative period. Inhaled nitric oxide was also administered if the patient was kept intubated 12 hours after surgery. Early postoperative outcome was compared with a historical cohort of 32 patients on whom the modified Fontan procedure was performed between March, 2000 and December, 2009. Postoperative administration of sildenafil and nitric oxide had no influence on early postoperative outcome after the modified Fontan procedure in terms of duration of pleural effusions, mechanical ventilation time, length of stay in the ICU, and length of hospital stay.
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