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Estudio comparativo de RetCam II frente a oftalmoscopia binocular en el cribado de la retinopatía de la prematuridad. [artículo]

Por: Tejada Palacios, Pilar [Oftalmología] | Zarratea, L [Oftalmología] | Moral Pumarega, María Teresa [Neonatología] | Cruz Bértolo, Javier de la [Epidemiología Clínica].
Colaborador(es): Servicio de Pediatría-Neonatología | Servicio de Oftalmología | Instituto de Investigación imas12.
Tipo de material: materialTypeLabelArtículoEditor: Archivos de la Sociedad Española de Oftalmología, 2015Descripción: 90(8):373-8.Recursos en línea: Solicitar documento Resumen: Objective: To determine the performance of RetCam vs. binocular ophthalmoscopy (BIO) in a screening program for retinopathy of prematurity (ROP). Methods: Observational comparative study with prospective data collection. Examinations with RetCam (n=169) were performed on 83 infants included in a screening program for ROP and stored for analysis at a later stage. An experienced ophthalmologist examined the ocular fundus with binocular indirect ophthalmoscopy (BIO). The RetCam images were assessed for the presence of ROP, zone, grade, and presence of plus disease. RetCam and BIO data were compared by visually to estimate sensitivity, specificity, positive (VPP) and negative (VPN) predictive values. Results: ROP disease was detected in 108 eyes with BIO, and in 74 with RetCam. Out of 306 eyes examined with RetCam, false negative results were found in 34 eyes, with no false positives. Sensitivity of RetCam exam vs. BIO was 0.68, and specificity was 0.99. Positive predictive value was 0.93 and negative predictive value was 0.85. All 34 ROP cases not detected with RetCam were in zone III or outer zone II. They were all mild and regressed spontaneously. No threshold ROP was missed with RetCam. Conclusion: Binocular indirect ophthalmoscopy is the reference method for the diagnosis of ROP. RetCam may be used as an alternative for ROP screening.
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Formato Vancouver:
Tejada Palacios P, Zarratea L, Moral M, de la Cruz Bértolo J. Estudio comparativo de RetCam II frente a oftalmoscopia binocular en el cribado de la retinopatía de la prematuridad. Arch Soc Esp Oftalmol. 2015 Aug;90(8):373-8.

PMID: 25817958

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Objective: To determine the performance of RetCam vs. binocular ophthalmoscopy (BIO) in a screening program for retinopathy of prematurity (ROP).
Methods: Observational comparative study with prospective data collection. Examinations with RetCam (n=169) were performed on 83 infants included in a screening program for ROP and stored for analysis at a later stage. An experienced ophthalmologist examined the ocular fundus with binocular indirect ophthalmoscopy (BIO). The RetCam images were assessed for the presence of ROP, zone, grade, and presence of plus disease. RetCam and BIO data were compared by visually to estimate sensitivity, specificity, positive (VPP) and negative (VPN) predictive values.
Results: ROP disease was detected in 108 eyes with BIO, and in 74 with RetCam. Out of 306 eyes examined with RetCam, false negative results were found in 34 eyes, with no false positives. Sensitivity of RetCam exam vs. BIO was 0.68, and specificity was 0.99. Positive predictive value was 0.93 and negative predictive value was 0.85. All 34 ROP cases not detected with RetCam were in zone III or outer zone II. They were all mild and regressed spontaneously. No threshold ROP was missed with RetCam.
Conclusion: Binocular indirect ophthalmoscopy is the reference method for the diagnosis of ROP. RetCam may be used as an alternative for ROP screening.

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