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Cannabis abuse effects on prepulse inhibition in patients with first episode psychosis in schizophrenia. [artículo]

Por: Morales Muñoz, Isabel [Psiquiatría] | Jurado Barba, Rosa [Psiquiatría] | Caballero González, Montserrat [Psiquiatría] | Rodríguez Jiménez, Roberto [Psiquiatría] | Jiménez Arriero, Miguel Ángel [Psiquiatría] | Rubio Valladolid, Gabriel [Psiquiatría].
Colaborador(es): Servicio de Psiquiatría.
Tipo de material: materialTypeLabelArtículoEditor: The Journal of neuropsychiatry and clinical neurosciences, 2015Descripción: 27(1):48-53.Recursos en línea: Solicitar documento Resumen: Deficits in prepulse inhibition (PPI) and cannabis abuse are consistently found in schizophrenia. The authors studied PPI deficits in first episode psychosis (FEP) with schizophrenia and cannabis abuse influence. Thirty-five patients with FEP and 22 control subjects were examined. Patients were divided into cannabis use disorder (CUD) (N=21) and non-CUD (N=14). Startle measures were as follows: PPI at 30, 60, and 120 msec. Patients with CUD and patients without CUD showed lower PPI at 30 msec than control subjects. At 60 msec, patients with CUD obtained higher %PPI than patients without CUD, and patients without CUD obtained lower levels than control subjects. These findings show that cannabis abuse may improve PPI in patients with FEP at some levels.
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Artículo Artículo PC16831 (Navegar estantería) Disponible

Formato Vancouver:
Morales Muñoz I, Jurado Barba R, Caballero M, Rodríguez Jiménez R, Jiménez Arriero MÁ, Fernández Guinea S et al. Cannabis abuse effects on prepulse inhibition in patients with first episode psychosis in schizophrenia. J Neuropsychiatry Clin Neurosci. 2015 Winter;27(1):48-53.

PMID: 25716487

Contiene 54 referencias

Deficits in prepulse inhibition (PPI) and cannabis abuse are consistently found in schizophrenia. The authors studied PPI deficits in first episode psychosis (FEP) with schizophrenia and cannabis abuse influence. Thirty-five patients with FEP and 22 control subjects were examined. Patients were divided into cannabis use disorder (CUD) (N=21) and non-CUD (N=14). Startle measures were as follows: PPI at 30, 60, and 120 msec. Patients with CUD and patients without CUD showed lower PPI at 30 msec than control subjects. At 60 msec, patients with CUD obtained higher %PPI than patients without CUD, and patients without CUD obtained lower levels than control subjects. These findings show that cannabis abuse may improve PPI in patients with FEP at some levels.

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