Utilidad de la manometría de alta resolución en el diagnóstico de la disrupción de la unión gastroesofágica: causas que influyen en su disrupción y asociación con reflujo gastroesofágico y alteraciones manométricas. [artículo]
Por: Ciriza de los Ríos, Constanza [Aparato Digestivo]
| Canga Rodríguez-Valcárcel, Fernando [Aparato Digestivo] | Castel de Lucas, Isabel [Aparato Digestivo] | Lora Pablos, David [Instituto Investigación I+12] | Cruz Bértolo, Javier de la [Epidemiología Clínica] | Castellano Tortajada, Gregorio [Aparato Digestivo].
Colaborador(es): Servicio de Medicina del Aparato Digestivo | Instituto de Investigación imas12.
Tipo de material: 
ArtículoEditor: Revista española de enfermedades digestivas : órgano oficial de la Sociedad Española de Patología Digestiva, 2014Descripción: 106(1)22-9.Recursos en línea: Solicitar documento Resumen: Background: High-resolution manometry (HRM) is a
breakthrough in the morphological study of the gastroesophageal junction (GEJ) and its degrees of disruption.
Objectives: a) Assessment of risk factors involved in the
disruption of the GEJ in patients with gastroesophageal reflux (GER)
symptoms; b) the relationship between the type of GEJ and GER
demonstrated by 24 hours pH-monitoring; and c) identification
of the alterations in the manometric parameters related to the
morphology of the GEJ.
Methods: One hundred and fifteen patients with symptoms of
GER studied with HRM and classified by the type of GEJ (type I: Normal; type II: Sliding; type III: Hiatal hernia). Twenty four hour pH-monitoring without proton pump inhibitors was performed in all of them. Epidemiological aspects, manometric parameters (Chicago 2012 classification) and the pH-onitoring results were evaluated.
Results: Age (OR 1.033 [1.006-1.060]; p = 0.16), BMI (OR
1.097 [1.022-1.176]; p = 0. 01) and abdominal perimeter (OR
1.034 [1.005-1.063]; p = 0.0215) were independent risk factors
for the GEJ type III (area under the curve 0.70). Disruption of the GEJ was associated with a lower resting pressure (p = 0.006), greater length (p < 0.001) and greater esophageal shortening (p < 0.001). Abnormal acidic reflux was found in the total period (p = 0.015), standing (p = 0.022) and supine (p = 0.001) in patients with GEJ type II and III with respect to type I.
Conclusions: Increased age, overweight and central
obesity pose a higher risk of GEJ type III (hiatal hernia). The
greater disruption of the GEJ is associated with lower resting
pressure, esophageal shortening, and higher acid exposure in the pH-monitoring.
| Tipo de ítem | Ubicación actual | Signatura | Estado | Fecha de vencimiento |
|---|---|---|---|---|
Artículo
|
PC16692 (Navegar estantería) | Disponible |
Formato Vancouver:
Ciriza de los Ríos C, Canga Rodríguez-Valcárcel F, Castel de Lucas I, Castellano Tortajada G. Utilidad de la manometría de alta resolución en el diagnóstico de la disrupción de la unión gastroesofágica: causas que influyen en su disrupción y asociación con reflujo gastroesofágico y alteraciones manométricas. Rev Esp Enferm Dig. 2014 Jan;106(1)22-9.
PMID: 24689712
Contiene 21 referencias
Background: High-resolution manometry (HRM) is a
breakthrough in the morphological study of the gastroesophageal junction (GEJ) and its degrees of disruption.
Objectives: a) Assessment of risk factors involved in the
disruption of the GEJ in patients with gastroesophageal reflux (GER)
symptoms; b) the relationship between the type of GEJ and GER
demonstrated by 24 hours pH-monitoring; and c) identification
of the alterations in the manometric parameters related to the
morphology of the GEJ.
Methods: One hundred and fifteen patients with symptoms of
GER studied with HRM and classified by the type of GEJ (type I: Normal; type II: Sliding; type III: Hiatal hernia). Twenty four hour pH-monitoring without proton pump inhibitors was performed in all of them. Epidemiological aspects, manometric parameters (Chicago 2012 classification) and the pH-onitoring results were evaluated.
Results: Age (OR 1.033 [1.006-1.060]; p = 0.16), BMI (OR
1.097 [1.022-1.176]; p = 0. 01) and abdominal perimeter (OR
1.034 [1.005-1.063]; p = 0.0215) were independent risk factors
for the GEJ type III (area under the curve 0.70). Disruption of the GEJ was associated with a lower resting pressure (p = 0.006), greater length (p < 0.001) and greater esophageal shortening (p < 0.001). Abnormal acidic reflux was found in the total period (p = 0.015), standing (p = 0.022) and supine (p = 0.001) in patients with GEJ type II and III with respect to type I.
Conclusions: Increased age, overweight and central
obesity pose a higher risk of GEJ type III (hiatal hernia). The
greater disruption of the GEJ is associated with lower resting
pressure, esophageal shortening, and higher acid exposure in the pH-monitoring.
No hay comentarios para este ejemplar.