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Use of cohort data to estimate national prevalence of transmitted drug resistance to antiretroviral drugs in Spain (2007-2012). [artículo]

Por: Delgado Vázquez, Rafael [Microbiología y Parasitología].
Colaborador(es): Servicio de Microbiología y Parasitología.
Tipo de material: materialTypeLabelArtículoEditor: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2014Descripción: 21(1):105.e1-5.Recursos en línea: Solicitar documento Resumen: Prevalence of transmitted drug resistance (pTDR) to antiretroviral drugs in Spain (2007-2012) was estimated using the CoRIS cohort, adjusting its territorial distribution and transmission route to the reference population from the Spanish Information System on New human immunodeficiency virus diagnoses. A total of 2702 patients from ten autonomous communities and with naive FASTA sequence within 6 months of human immunodeficiency virus diagnosis were selected. Weighted pTDR, estimated using the inverse probability of selection in the sample by autonomous communities and transmission group, was 8.12% (95% CI 6.44-9.80), not significantly different from unweighted pTDR. We illustrate how proportional weighting can maximize representativeness of cohort-based data, and its value to monitor pTDR at country level.
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Artículo Artículo PC16689 (Navegar estantería) Disponible

Formato Vancouver:
Monge S, Díez M, Alvárez M, Guillot V, Iribarren JA, Palacios R et al; Cohorte de la Red de Investigación en Sida (CoRIS). Use of cohort data to estimate national prevalence of transmitted drug resistance to antiretroviral drugs in Spain (2007-2012). Clin Microbiol Infect. 2015 Jan;21(1):105.e1-5.

PMID: 25636937

Contiene 18 referencias

Prevalence of transmitted drug resistance (pTDR) to antiretroviral drugs in Spain (2007-2012) was estimated using the CoRIS cohort, adjusting its territorial distribution and transmission route to the reference population from the Spanish Information System on New human immunodeficiency virus diagnoses. A total of 2702 patients from ten autonomous communities and with naive FASTA sequence within 6 months of human immunodeficiency virus diagnosis were selected. Weighted pTDR, estimated using the inverse probability of selection in the sample by autonomous communities and transmission group, was 8.12% (95% CI 6.44-9.80), not significantly different from unweighted pTDR. We illustrate how proportional weighting can maximize representativeness of cohort-based data, and its value to monitor pTDR at country level.

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