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Erectile dysfunction but not hormonal levels are related to higher estimated mortality risk using charlson comorbidity index. [artículo]

Por: Romero Otero, Javier [Urología].
Colaborador(es): Servicio de Urología.
Tipo de material: materialTypeLabelArtículoEditor: Journal of men's health, 2014Descripción: 11(3):109-14.Recursos en línea: Solicitar documento Resumen: Background: The main purpose of the study is to analyze the correlation between erectile function and hormonal pattern with 10-year mortality risk using the Charlson Comorbidity Index (CCI). Methods: A cross-sectional analysis of 180 consecutive men attending a Sexual Medicine and Men’s Health outpatient clinic between July 2010 and July 2011 was conducted. Inclusion criteria were age over 18 years old, no history of pelvic surgery or radio- or cryotherapy and no treatment with gonadotropin-releasing hormone analogues or antiandrogenic drugs. Variables including age, height, weight, body mass index, CCI, Erection Hardness Score (EHS) questionnaire, hormonal pattern (testosterone [T] and sex-hormone-binding globulin [SHBG]), and biochemical data were prospectively recorded. Free and bioavailable testosterones were calculated using Vermeulen’s formula. Low T levels were defined as T < 346 ng/dL. A multivariate analysis was performed of the relationship between the study population’s variables and the 10-year mortality risk. Both erectile dysfunction (ED) and low testosterone levels have been related to entities affecting cardiovascular health, such as diabetes, metabolic syndrome, and heart disease. CCI is a validated tool to predict mortality, using a 17-items tool to predict 10-year mortality risk. Results: One hundred and eighty patients were included. The mean age was 55 – 12 years old. The rate of ED was 84%. Low T levels were found in 22.8 % of men. In the univariate analysis, the variables of age ( p = 0.001), ED ( p = 0.001), EHS ( p = 0.001), and C-reactive protein ( p = 0.019) were related to higher mortality risks according to CCI. In the multivariate analysis, the variables of age ( p = 0.001), C-reactive protein ( p = 0.022), and ED ( p = 0.04) were related to higher mortality risks. Conclusion: Age, C-reactive protein, and ED are related to higher estimated 10-year mortality risk using CCI.
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Formato Vancouver:
García Cruz E, Gosálbez D, Sallent A, Piqueras M, Leibar Tamayo A, Romero Otero J et al. Erectile dysfunction but not hormonal levels are related to higher estimated mortality risk using charlson comorbidity index. J Mens Health. 2014;11(3):109-14

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Contiene 28 referencias

Background: The main purpose of the study is to analyze the correlation between erectile function and
hormonal pattern with 10-year mortality risk using the Charlson Comorbidity Index (CCI).
Methods: A cross-sectional analysis of 180 consecutive men attending a Sexual Medicine and Men’s Health
outpatient clinic between July 2010 and July 2011 was conducted. Inclusion criteria were age over 18 years old,
no history of pelvic surgery or radio- or cryotherapy and no treatment with gonadotropin-releasing hormone
analogues or antiandrogenic drugs. Variables including age, height, weight, body mass index, CCI, Erection
Hardness Score (EHS) questionnaire, hormonal pattern (testosterone [T] and sex-hormone-binding globulin
[SHBG]), and biochemical data were prospectively recorded. Free and bioavailable testosterones were calculated
using Vermeulen’s formula. Low T levels were defined as T < 346 ng/dL. A multivariate analysis was
performed of the relationship between the study population’s variables and the 10-year mortality risk. Both
erectile dysfunction (ED) and low testosterone levels have been related to entities affecting cardiovascular
health, such as diabetes, metabolic syndrome, and heart disease. CCI is a validated tool to predict mortality,
using a 17-items tool to predict 10-year mortality risk.
Results: One hundred and eighty patients were included. The mean age was 55 – 12 years old. The rate of ED
was 84%. Low T levels were found in 22.8 % of men. In the univariate analysis, the variables of age
( p = 0.001), ED ( p = 0.001), EHS ( p = 0.001), and C-reactive protein ( p = 0.019) were related to higher mortality
risks according to CCI. In the multivariate analysis, the variables of age ( p = 0.001), C-reactive protein
( p = 0.022), and ED ( p = 0.04) were related to higher mortality risks.
Conclusion: Age, C-reactive protein, and ED are related to higher estimated 10-year mortality risk using CCI.

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