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Efficacy and safety of the use of heparin as thromboprophylaxis in patients with liver cirrhosis: A systematic review and meta-analysis. [artículo]

Por: Bisbal Pardo, Otilia [Medicina Interna] | Gómez Cuervo, Covadonga [Medicina Interna] | Pérez-Jacoiste Asín, María Asunción [Medicina Interna].
Colaborador(es): Servicio de Medicina Interna.
Editor: Thrombosis research, 2013Descripción: 132(4):414-9.Recursos en línea: Solicitar documento Resumen: INTRODUCTION: Venous thromboembolism is a common cause of morbidity and mortality. Although cirrhosis has classically been considered as an acquired bleeding diathesis, there is increasing evidence that rejects the traditional belief that these patients are naturally protected against venous thromboembolism. However, antithrombotic prophylaxis in this setting is still underused. The aim of this review is to assess if the use of heparin in cirrhotic patients is effective in the prevention of venous thromboembolism and whether its use is related to an increase in bleeding episodes.
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Formato Vancouver:
Gómez Cuervo C, Bisbal Pardo O, Pérez-Jacoiste Asín MA. Efficacy and safety of the use of heparin as thromboprophylaxis in patients with liver cirrhosis: a systematic review and meta-analysis. Thromb Res. 2013 Oct;132(4):414-9.

PMID: 23993900

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INTRODUCTION: Venous thromboembolism is a common cause of morbidity and mortality. Although cirrhosis has classically been considered as an acquired bleeding diathesis, there is increasing evidence that rejects the traditional belief that these patients are naturally protected against venous thromboembolism. However, antithrombotic prophylaxis in this setting is still underused. The aim of this review is to assess if the use of heparin in cirrhotic patients is effective in the prevention of venous thromboembolism and whether its use is related to an increase in bleeding episodes.

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