Malaria hidden in a patient with diffuse large-B-cell lymphoma and sickle-cell trait [artículo]
Por: Martínez González, Miguel Ángel [Anatomía Patológica]
| Martínez López, Joaquín [Hematología y Hemoterapia].
Colaborador(es): Servicio de Anatomía Patológica | Servicio de Hematología y Hemoterapia | Instituto de Investigación imas12.
Editor: Journal of Clinical Microbiology, 2011Descripción: 49(12):4401-4404. Tipo de medio: Recursos en línea: Solicitar documento Resumen: We report a case of an African patient with sickle cell trait who was diagnosed in Spain with B-cell lymphoma. Blood smears were negative for malaria, and no plasmodium antigens were detected in the blood. To treat his lymphoma, the patient underwent chemotherapy and autologous stem cell transplantation. Following a splenectomy due to a worsening condition, he developed clinical malaria with detectable parasitemia. This case suggests that the humoral response and parasite removal by the spleen may afford protection from overt disease and may even help maintain subclinical human reservoirs of the disease.
| Tipo de ítem | Ubicación actual | Signatura | Estado | Fecha de vencimiento |
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Artículo
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PC10525 (Navegar estantería) | Disponible |
Navegando Hospital Universitario 12 de Octubre Estantes Cerrar el navegador de estanterías
Formato Vancouver:
Linares M, Albizua E, Méndez D, Rubio JM, Martínez-Serna A, Martínez MA, et al. Malaria hidden in a patient with diffuse large-B-cell lymphoma and sickle-cell trait. J Clin Microbiol. 2011;49(12):4401-4.
PMID:21976762
Contiene 22 refencias.
We report a case of an African patient with sickle cell trait who was diagnosed in Spain with B-cell lymphoma. Blood smears were negative for malaria, and no plasmodium antigens were detected in the blood. To treat his lymphoma, the patient underwent chemotherapy and autologous stem cell transplantation. Following a splenectomy due to a worsening condition, he developed clinical malaria with detectable parasitemia. This case suggests that the humoral response and parasite removal by the spleen may afford protection from overt disease and may even help maintain subclinical human reservoirs of the disease.
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