Algorithm proposal based on the C. Diff Quik Chek Complete ICT device for detecting Clostridium difficile infection [artículo]
Por: Orellana Miguel, María Ángeles [Microbiología y Parasitología]
| Alcolea Medina, Adela [Microbiología] | Barrado Blanco, Laura [Microbiología y Parasitología] | Rodríguez Otero, Joaquín [Microbiología y Parasitología] | Chaves Sánchez, Fernando [Microbiología y Parasitología].
Colaborador(es): Servicio de Microbiología y Parasitología.
Editor: Enfermedades Infecciosas y Microbiología Clínica, 2013Descripción: 31(2):97-99.Recursos en línea: Solicitar documento Resumen: Resumen:
Objective: To assess a new immunochromatography (ICT) test that detects glutamate dehydrogenase (GDH) antigen and Clostridium difficile toxin A/B simultaneously, and to propose an algorithm for the diagnosis of C difficile infection (CDI) based on this test. Methods: We analysed 970 stool samples. Discrepant results between GDH and toxin A/B were resolved using toxigenic culture as the reference. Results: This test enabled us to obtain a conclusive result in <30 min in 93.8% of the samples. Among the discrepant results (GDH (+)/Toxin A/B (-)), 41.7% (25/60) were found to be toxigenic C dfficile by toxigenic culture. Conclusion: This test has a high sensitivity and specificity for the diagnosis of CDI.
| Tipo de ítem | Ubicación actual | Signatura | Estado | Fecha de vencimiento |
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Artículo
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PC10262 (Navegar estantería) | Disponible |
Formato Vancouver:
Orellana Miguel MA, Alcolea Medina A, Barrado Blanco L, Rodríguez Otero J, Chaves Sánchez F. Algorithm proposal based on the C. Diff Quik Chek Complete ICT device for detecting Clostridium difficile infection. Enferm Infecc Microbiol
Clin. 2013;31(2):97-9.
Contiene 13 referencias, 1 figura y 1 tabla.
Resumen:
Objective: To assess a new immunochromatography (ICT) test that detects glutamate dehydrogenase (GDH) antigen and Clostridium difficile toxin A/B simultaneously, and to propose an algorithm for the diagnosis of C difficile infection (CDI) based on this test. Methods: We analysed 970 stool samples. Discrepant results between GDH and toxin A/B were resolved using toxigenic culture as the reference. Results: This test enabled us to obtain a conclusive result in <30 min in 93.8% of the samples. Among the discrepant results (GDH (+)/Toxin A/B (-)), 41.7% (25/60) were found to be toxigenic C dfficile by toxigenic culture. Conclusion: This test has a high sensitivity and specificity for the diagnosis of CDI.
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