Arribas Ynsaurriaga, Fernando Cerezo Olmos, César Fontenla Cerezuela, Adolfo García Donaire, José Antonio Hernández Hernández, Felipe Ruilope Urioste, Luis Miguel Salgado Aranda, Ricardo Segura de la Morena, Julián
Management of Resistant Hypertension in a Multidisciplinary Unit of Renal Denervation: Protocol and Results. [artículo] - Revista española de cardiología, 2013 - 66(5):364-70.
Formato Vancouver:
Fontenla A, García-Donaire JA, Hernández F, Segura J, Salgado R, Cerezo C et al. Management of resistant hypertension in a multidisciplinary unit of renal denervation: protocol and results. Rev Esp Cardiol (Engl Ed). 2013 May;66(5):364-70.
PMID: 24775818
Contiene 18 referencias
INTRODUCTION AND OBJECTIVES: Resistant hypertension is a clinical problem because of its difficult management and increased morbidity and mortality. Catheter-based renal denervation has been demonstrated to improve control in these patients. The results of establishing a multidisciplinary unit for the implementation of renal denervation in the management of resistant hypertension are described. METHODS: A team of nephrologists and cardiologists created a protocol for patient selection, intervention, and follow-up. One hundred and ninety-seven patients with poorly controlled essential hypertension, despite taking 3 or more drugs, were included. The ablation technique previously described was supported by a navigator based on rotational angiography. Blood pressure at baseline and after follow-up was compared using the Wilcoxon test for paired samples. RESULTS: One hundred and eight patients (55%) with pseudo-resistant hypertension were excluded. The other 89 were given antialdosteronic drugs, to which 60 patients (30%) responded. The remaining 29 patients (15%) were candidates for denervation. Eleven patients, with blood pressure 164/99mmHg and taking 4.4 antihypertensive drugs, were ablated. After 72 days of follow-up, systolic and diastolic blood pressure fell by 25 mmHg (P=.02) and 10 mmHg (P=.06), respectively. In 10 patients (91%) at least 1 drug was discontinued. CONCLUSIONS: Renal denervation performed by a multidisciplinary team led to an improvement in blood pressure similar to previous studies, with a greater reduction of antihypertensive drugs.
Management of Resistant Hypertension in a Multidisciplinary Unit of Renal Denervation: Protocol and Results. [artículo] - Revista española de cardiología, 2013 - 66(5):364-70.
Formato Vancouver:
Fontenla A, García-Donaire JA, Hernández F, Segura J, Salgado R, Cerezo C et al. Management of resistant hypertension in a multidisciplinary unit of renal denervation: protocol and results. Rev Esp Cardiol (Engl Ed). 2013 May;66(5):364-70.
PMID: 24775818
Contiene 18 referencias
INTRODUCTION AND OBJECTIVES: Resistant hypertension is a clinical problem because of its difficult management and increased morbidity and mortality. Catheter-based renal denervation has been demonstrated to improve control in these patients. The results of establishing a multidisciplinary unit for the implementation of renal denervation in the management of resistant hypertension are described. METHODS: A team of nephrologists and cardiologists created a protocol for patient selection, intervention, and follow-up. One hundred and ninety-seven patients with poorly controlled essential hypertension, despite taking 3 or more drugs, were included. The ablation technique previously described was supported by a navigator based on rotational angiography. Blood pressure at baseline and after follow-up was compared using the Wilcoxon test for paired samples. RESULTS: One hundred and eight patients (55%) with pseudo-resistant hypertension were excluded. The other 89 were given antialdosteronic drugs, to which 60 patients (30%) responded. The remaining 29 patients (15%) were candidates for denervation. Eleven patients, with blood pressure 164/99mmHg and taking 4.4 antihypertensive drugs, were ablated. After 72 days of follow-up, systolic and diastolic blood pressure fell by 25 mmHg (P=.02) and 10 mmHg (P=.06), respectively. In 10 patients (91%) at least 1 drug was discontinued. CONCLUSIONS: Renal denervation performed by a multidisciplinary team led to an improvement in blood pressure similar to previous studies, with a greater reduction of antihypertensive drugs.
