Caso, Javier Rubén García Bueno, Borja Hinojosa, Ara E Leza, Juan Carlos Madrigal, José LM
Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators. [artículo] - Journal of neuroinflammation, 2013 - 10:81.
Formato Vancouver:
Hinojosa AE, Caso JR, García-Bueno B, Leza JC, Madrigal JL. Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators. J Neuroinflammation. 2013 Jul 9;10:81.
PMID: 23837880
Contiene 65 referencias
Noradrenaline (NA) is known to limit neuroinflammation. However, the previously described induction by NA of a chemokine involved in the progression of immune/inflammatory processes, such as chemokine (C-C motif) ligand 2 (CCL2)/monocyte chemotactic protein-1 (MCP-1), apparently contradicts NA anti-inflammatory actions. In the current study we analyzed NA regulation of astroglial chemokine (C-X3-C motif) ligand 1 (CX3CL1), also known as fractalkine, another chemokine to which both neuroprotective and neurodegenerative actions have been attributed. In addition, NA effects on other chemokines and pro-inflammatory mediators were also analyzed.
Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators. [artículo] - Journal of neuroinflammation, 2013 - 10:81.
Formato Vancouver:
Hinojosa AE, Caso JR, García-Bueno B, Leza JC, Madrigal JL. Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators. J Neuroinflammation. 2013 Jul 9;10:81.
PMID: 23837880
Contiene 65 referencias
Noradrenaline (NA) is known to limit neuroinflammation. However, the previously described induction by NA of a chemokine involved in the progression of immune/inflammatory processes, such as chemokine (C-C motif) ligand 2 (CCL2)/monocyte chemotactic protein-1 (MCP-1), apparently contradicts NA anti-inflammatory actions. In the current study we analyzed NA regulation of astroglial chemokine (C-X3-C motif) ligand 1 (CX3CL1), also known as fractalkine, another chemokine to which both neuroprotective and neurodegenerative actions have been attributed. In addition, NA effects on other chemokines and pro-inflammatory mediators were also analyzed.
