Galindo Izquierdo, Alberto Gómez Arriaga, Paula Isabel Herráiz García, Ignacio Núñez Enamorado, Noemí Puente Águeda, José Manuel Zamora Crespo, Zamora
Mid-term neurodevelopmental outcome in isolated mild ventriculomegaly diagnosed in fetal life [artículo] - Fetal Diagnosis and Therapy, 2012 - 31(1):12-18.
Formato Vancouver:
Gómez-Arriaga P, Herraiz I, Puente JM, Zamora-Crespo B, Núñez-Enamorado N, Galindo A. Mid-term neurodevelopmental outcome in isolated mild ventriculomegaly diagnosed in fetal life. Fetal Diagn Ther. 2012;31(1):12-8.
PMID: 22178749
Contiene 29 referencias
To analyze mid-term neurodevelopment outcome in children with isolated mild ventriculomegaly (VM) ≤12 mm diagnosed in fetal life, using the Battelle Developmental Inventory Screening Test (BDIST).
METHODS: 86 cases of mild VM were identified. 68 were excluded due to: other cerebral anomalies (n = 40), extra-cerebral anomalies (n = 3), chromosomal defects (n = 4), dysmorphic syndromes (n = 4), congenital infections (n = 2), termination of pregnancy (n = 9), stillbirth (n = 2) and incomplete follow-up (n = 4). 18 cases (range 1-8 years) of isolated mild VM were included for analysis. Seven neurodevelopment domains were assessed by BDIST.
RESULTS: Routine neuropediatrical evaluation detected neurological disorders in five children (28%; 3 with language impairment, one left hemiparesis and one intellectual retardation). BDIST showed some degree of neurodevelopmental delay in higher proportions: 66% in social-personal skills, 56% in gross motor skills, 39% in adaptive behavior and 28% in fine motor skills. Communicative and cognitive areas were the least affected (11 and 22% had moderate-to-severe involvement, respectively). A general trend towards worse outcomes was observed in the group of ≥4 years, although significant differences were only found for gross motor skills.
CONCLUSION: Subtle neurological delays may appear during the infant period in fetuses prenatally diagnosed of isolated mild VM. In consequence, adequate measures should be established for early detection and treatment.
Mid-term neurodevelopmental outcome in isolated mild ventriculomegaly diagnosed in fetal life [artículo] - Fetal Diagnosis and Therapy, 2012 - 31(1):12-18.
Formato Vancouver:
Gómez-Arriaga P, Herraiz I, Puente JM, Zamora-Crespo B, Núñez-Enamorado N, Galindo A. Mid-term neurodevelopmental outcome in isolated mild ventriculomegaly diagnosed in fetal life. Fetal Diagn Ther. 2012;31(1):12-8.
PMID: 22178749
Contiene 29 referencias
To analyze mid-term neurodevelopment outcome in children with isolated mild ventriculomegaly (VM) ≤12 mm diagnosed in fetal life, using the Battelle Developmental Inventory Screening Test (BDIST).
METHODS: 86 cases of mild VM were identified. 68 were excluded due to: other cerebral anomalies (n = 40), extra-cerebral anomalies (n = 3), chromosomal defects (n = 4), dysmorphic syndromes (n = 4), congenital infections (n = 2), termination of pregnancy (n = 9), stillbirth (n = 2) and incomplete follow-up (n = 4). 18 cases (range 1-8 years) of isolated mild VM were included for analysis. Seven neurodevelopment domains were assessed by BDIST.
RESULTS: Routine neuropediatrical evaluation detected neurological disorders in five children (28%; 3 with language impairment, one left hemiparesis and one intellectual retardation). BDIST showed some degree of neurodevelopmental delay in higher proportions: 66% in social-personal skills, 56% in gross motor skills, 39% in adaptive behavior and 28% in fine motor skills. Communicative and cognitive areas were the least affected (11 and 22% had moderate-to-severe involvement, respectively). A general trend towards worse outcomes was observed in the group of ≥4 years, although significant differences were only found for gross motor skills.
CONCLUSION: Subtle neurological delays may appear during the infant period in fetuses prenatally diagnosed of isolated mild VM. In consequence, adequate measures should be established for early detection and treatment.