Miranda Utrera, Natalia Medina Polo, José Pamplona Casamayor, Manuel Passas Martínez, Juan Rodríguez Antolín, Alfredo Rosa Kehrman, Federico de la Duarte Ojeda, José Manuel Tejido Sánchez, Ángel Villacampa Aubá, Felipe Andrés Belmonte, Amado
Donantes en asistolia no controlada (tipos i-ii) con recirculación normotérmica versus donantes en muerte cerebral: evaluación de resultados funcionales y supervivencia. [artículo] - Actas urológicas españolas, 2015 - 39(7):429-34.
Formato Vancouver:
Miranda Utrera N, Medina Polo J, Pamplona Casamayor M, Passas Martínez JB, Rodríguez Antolín A, de la Rosa Kehrmann F et al. Donantes en asistolia no controlada (tipos i-ii) con recirculación normotérmica versus donantes en muerte cerebral: evaluación de resultados funcionales y supervivencia. Actas Urol Esp. 2015 Sep;39(7):429-34.
PMID: 25749460
Contiene 22 referencias
Objective: Non-heartbeating donors (NHBD) are an alternative to heartbeating donors (HBD). Our objective was to compare functional results and kidney survival from NHBDs and HBDs.
Material and methods: A retrospective study comparing the results of 236 normothermically preserved kidneys from type i and ii type NHBDs with the results of 250 from HBDs that were transplanted in our center between 2005 and 2012. Homogeneity between groups was tested and we evaluated the presence of delayed graft function (DGF) associated with pretransplant variables of the donor and recipient.
Results: Both groups show homogeneity in pretransplant characteristics in terms of: age, HLA incompatibilities, and recipient hemodialysis time. Average follow-up time was 33 months (range 0-87) for NHBDs and 38 months (range 0-90) for HBDs. 5.5% of NHBDs showed primary non-function (PNF) vs. 4% of HBDs (P=.42) and 80.9% of DGF vs. 46.8% of HBDs (P<.001). At the end of the follow-up, there were no statistically significant differences in the survival of grafts (92.8% for NHBD vs. 93.6% for HBD, P=.71) and recipients (99.1% NHBD vs. 98.6% HBD, P=.28).
Conclusions: Although the DGF percentage was greater for NHBDs, final creatinine as well as graft and recipient survival were similar for both groups. Therefore, in our experience, kidneys from NHBDs have similar results to those from HBDs and are an excellent source of organs for transplantation.
Donantes en asistolia no controlada (tipos i-ii) con recirculación normotérmica versus donantes en muerte cerebral: evaluación de resultados funcionales y supervivencia. [artículo] - Actas urológicas españolas, 2015 - 39(7):429-34.
Formato Vancouver:
Miranda Utrera N, Medina Polo J, Pamplona Casamayor M, Passas Martínez JB, Rodríguez Antolín A, de la Rosa Kehrmann F et al. Donantes en asistolia no controlada (tipos i-ii) con recirculación normotérmica versus donantes en muerte cerebral: evaluación de resultados funcionales y supervivencia. Actas Urol Esp. 2015 Sep;39(7):429-34.
PMID: 25749460
Contiene 22 referencias
Objective: Non-heartbeating donors (NHBD) are an alternative to heartbeating donors (HBD). Our objective was to compare functional results and kidney survival from NHBDs and HBDs.
Material and methods: A retrospective study comparing the results of 236 normothermically preserved kidneys from type i and ii type NHBDs with the results of 250 from HBDs that were transplanted in our center between 2005 and 2012. Homogeneity between groups was tested and we evaluated the presence of delayed graft function (DGF) associated with pretransplant variables of the donor and recipient.
Results: Both groups show homogeneity in pretransplant characteristics in terms of: age, HLA incompatibilities, and recipient hemodialysis time. Average follow-up time was 33 months (range 0-87) for NHBDs and 38 months (range 0-90) for HBDs. 5.5% of NHBDs showed primary non-function (PNF) vs. 4% of HBDs (P=.42) and 80.9% of DGF vs. 46.8% of HBDs (P<.001). At the end of the follow-up, there were no statistically significant differences in the survival of grafts (92.8% for NHBD vs. 93.6% for HBD, P=.71) and recipients (99.1% NHBD vs. 98.6% HBD, P=.28).
Conclusions: Although the DGF percentage was greater for NHBDs, final creatinine as well as graft and recipient survival were similar for both groups. Therefore, in our experience, kidneys from NHBDs have similar results to those from HBDs and are an excellent source of organs for transplantation.
