Ochoa Parra, Nuria Navas Tejedor, Paula Morán Fernández, Laura Gómez Sánchez, Miguel Ángel
Inoperable chronic thromboembolic pulmonary hypertension treated with riociguat: A case study. [caso clínico] - Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2015 - 34(12):777.e1-5.
Formato Vancouver:
Ortiz Bautista C, Ochoa Parra N, Navas Tejedor P, Morán Fernández L, Gómez Sánchez MÁ. Inoperable chronic thromboembolic pulmonary hypertension treated with riociguat: A case study. Rev Port Cardiol. 2015 Dec;34(12):777.e1-5.
PMID: 26632111
Contiene 9 referencias
A 51-year-old woman presented with a one-year history of progressive dyspnea, WHO functional class III-IV and exercise-related syncope. Transthoracic echocardiography and computed tomography pulmonary angiography were performed, leading to a diagnosis of pulmonary arterial hypertension. She was referred to our pulmonary hypertension unit, where a complete study was performed, including ventilation/perfusion scan, which was consistent with chronic thromboembolic pulmonary hypertension. Risk factors for this condition were excluded and therapeutic options were evaluated. Imaging studies showed distal pulmonary disease so pulmonary endarterectomy was rejected. Further therapeutic options were evaluated and the patient was subsequently enrolled in an open-label uncontrolled trial with riociguat. After one year of treatment, significant improvement in functional class, 6-minute walk test and NT-proBNP were seen, without significant secondary effects.
Inoperable chronic thromboembolic pulmonary hypertension treated with riociguat: A case study. [caso clínico] - Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2015 - 34(12):777.e1-5.
Formato Vancouver:
Ortiz Bautista C, Ochoa Parra N, Navas Tejedor P, Morán Fernández L, Gómez Sánchez MÁ. Inoperable chronic thromboembolic pulmonary hypertension treated with riociguat: A case study. Rev Port Cardiol. 2015 Dec;34(12):777.e1-5.
PMID: 26632111
Contiene 9 referencias
A 51-year-old woman presented with a one-year history of progressive dyspnea, WHO functional class III-IV and exercise-related syncope. Transthoracic echocardiography and computed tomography pulmonary angiography were performed, leading to a diagnosis of pulmonary arterial hypertension. She was referred to our pulmonary hypertension unit, where a complete study was performed, including ventilation/perfusion scan, which was consistent with chronic thromboembolic pulmonary hypertension. Risk factors for this condition were excluded and therapeutic options were evaluated. Imaging studies showed distal pulmonary disease so pulmonary endarterectomy was rejected. Further therapeutic options were evaluated and the patient was subsequently enrolled in an open-label uncontrolled trial with riociguat. After one year of treatment, significant improvement in functional class, 6-minute walk test and NT-proBNP were seen, without significant secondary effects.
