Robles Díaz, Luis
Clinical guideline seom: hereditary colorectal cancer. [artículo] - Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2015 - 17(12):962-71.
Formato Vancouver:
Guillén Ponce C, Serrano R, Sánchez Heras AB, Teulé A, Chirivella I, Martín T et al. Clinical guideline seom: hereditary colorectal cancer. Clin Transl Oncol. 2015 Dec;17(12):962-71.
PMID: 26586118
PMC4689750
Contiene 43 referencias
Genetic mutations have been identified as the cause of inherited cancer risk in some colon cancer; these mutations are estimated to account for only 5-6 % of colorectal cancer (CRC) cases overall. Up to 25-30 % of patients have a family history of CRC that suggests a hereditary component, common exposures among family members, or a combination of both. Cancers in people with a hereditary predisposition typically occur at an earlier age than in sporadic cases. A predisposition to CRC may include a predisposition to other cancers, such as endometrial cancer. We describe genetics, current diagnosis and management of CRC hereditary syndromes pointing to a multidisciplinary approach to achieve the best results in patients and family outcomes.
Clinical guideline seom: hereditary colorectal cancer. [artículo] - Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2015 - 17(12):962-71.
Formato Vancouver:
Guillén Ponce C, Serrano R, Sánchez Heras AB, Teulé A, Chirivella I, Martín T et al. Clinical guideline seom: hereditary colorectal cancer. Clin Transl Oncol. 2015 Dec;17(12):962-71.
PMID: 26586118
PMC4689750
Contiene 43 referencias
Genetic mutations have been identified as the cause of inherited cancer risk in some colon cancer; these mutations are estimated to account for only 5-6 % of colorectal cancer (CRC) cases overall. Up to 25-30 % of patients have a family history of CRC that suggests a hereditary component, common exposures among family members, or a combination of both. Cancers in people with a hereditary predisposition typically occur at an earlier age than in sporadic cases. A predisposition to CRC may include a predisposition to other cancers, such as endometrial cancer. We describe genetics, current diagnosis and management of CRC hereditary syndromes pointing to a multidisciplinary approach to achieve the best results in patients and family outcomes.
